12 Uncommon Diabetes Symptoms and How to Deal With Them

Written by Jinfiniti Science on July 19, 2024. Posted in Diabetes, NAD, NAD+.

You probably know that diabetes can cause frequent urination, increased thirst, and tiredness.

But there are other less-obvious signs that might seem normal but could indicate high blood sugar levels.

These subtle symptoms are easy to overlook, yet spotting them early can be crucial for managing the condition effectively.

In this article, we discuss…

12 surprising diabetes symptoms that might be hiding in plain sight.

Practical lifestyle habits that can significantly slash your risk of developing diabetes.

How NAD benefits can play a crucial role in keeping your blood sugar levels optimized.

Diabetes is a chronic health condition that affects millions of people worldwide.

In fact, according to the World Health Organization (WHO), over 422 million people all over the world have diabetes¹, and the number is expected to rise.

In the United States alone, the Centers for Disease Control and Prevention (CDC) reports that 34.2 million Americans have diabetes, with approximately 1.5 million new cases diagnosed each year².

Diabetes does not discriminate, but certain populations are more vulnerable.

Adults over the age of 45, individuals with a family history of diabetes, and those with obesity are at higher risk.

These people have impaired insulin regulation, leading to persistent high blood sugar levels, known as hyperglycemia.

This can lead to serious health complications—such as cardiovascular disease, neuropathy (nerve damage), kidney damage, blindness, and diabetic ketoacidosis, to name a few—if not properly managed.

While many are familiar with the common symptoms of diabetes such as frequent urination, increased thirst, and fatigue, several lesser-known signs might indicate the presence of this condition.

Here are 12 uncommon signs of diabetes to be aware of:

1. Darkened Skin Patches (Acanthosis Nigricans)

Have you ever noticed dark, velvety patches on your skin, especially in areas like your neck, armpits, or groin?

This condition is known as acanthosis nigricans, and while it might seem harmless or just a cosmetic issue, it can actually be an important indicator of what’s happening inside your body.

When your skin develops these dark patches, it’s often a sign that your body is becoming resistant to insulin.

Insulin resistance is a condition where your body’s cells don’t respond properly to insulin, the hormone that regulates blood sugar.

When your cells resist insulin, your body needs to produce more of it to keep your blood sugar levels in check.

This overproduction can lead to higher levels of insulin in your blood, which then causes the skin cells to multiply faster than usual, resulting in those dark patches.

A study published in the Journal of Diabetes Care supports this connection, showing that acanthosis nigricans is frequently observed in individuals with insulin resistance and is often a precursor to type 2 diabetes.³

So, if you ever spot these dark patches on your skin, don’t just brush them off.

They could be an early warning sign that your body is struggling with insulin resistance, and it’s a good idea to get your blood sugar levels checked.

2. Frequent Yeast Infections

Frequent yeast infections aren’t just annoying—it could actually be a sign that something’s off with your blood sugar levels.

When your blood sugar is high, it creates the perfect environment for yeast to thrive. This is because yeast feeds on sugar, so the more sugar there is in your system, the more it can grow.

For women, this often means recurrent vaginal yeast infections. But it’s not just limited to that—both men and women can get skin infections or oral yeast infections, also known as thrush.

Therefore, if you notice you’re getting these infections more often than usual, it might be your body’s way of telling you to check your blood sugar.

A study published in the Journal of Clinical Investigation found that high blood sugar levels are closely linked to an increased risk of fungal infections⁴, including those caused by Candida, the type of yeast responsible for these infections .

So, if you’re experiencing frequent yeast infections, it’s worth talking to your doctor and getting your blood sugar levels tested.

3. Slow-Healing Wounds

Have you ever noticed that a small cut or bruise seems to be taking forever to heal?

It might be more than just a nuisance—it could be a sign that your blood sugar levels are higher than they should be.

When your blood sugar is elevated, it can really mess with your body’s ability to heal itself.

You see, high blood sugar can damage your blood vessels, reducing blood flow.

And good blood flow is essential for healing because it delivers the necessary nutrients and oxygen to the injured area.

If your blood sugar is consistently high, this impaired circulation means your cuts and bruises are not getting the help they need to heal quickly.

A study published in the Journal of Clinical Endocrinology & Metabolism found that people with higher blood sugar levels experienced slower wound healing due to the reduced function of their immune cells and poor circulation.⁵

So, if you find yourself dealing with wounds that seem to linger, it might be worth getting your blood sugar checked.

4. Tingling or Numbness in Hands and Feet (Peripheral Neuropathy)

Do you ever feel a strange tingling or numbness in your hands and feet, almost like a burning sensation?

This is something called peripheral neuropathy, and it’s pretty common in people with diabetes.

When your blood sugar stays elevated for too long, it can start to damage the nerves, especially in your extremities.

These nerves are super important for sending signals back and forth between your brain and the rest of your body. When they get damaged, you can start to feel that tingling, numbness, or even burning sensation.

And it’s not just a minor discomfort—it’s your body’s way of telling you that something’s up.

For example, a study published in Diabetes Care found a significant correlation between high blood sugar levels and the development of peripheral neuropathy.

They found that the longer your blood sugar is out of control, the more likely you are to develop this kind of nerve damage.⁶

5. Changes in Vision

When your blood sugar spikes and drops, it doesn’t just affect your energy levels—it can also impact your eyes.

High blood sugar levels cause the lenses in your eyes to swell, which changes their shape and how they focus light. This can lead to periodic blurriness or sudden shifts in how clearly you see things.

Think of your eye as a camera. If the lens isn’t the right shape, the pictures come out blurry. The same thing happens with your vision when your blood sugar is out of whack.

In fact, flactuation in your blood sugar levels can significantly affect the refractive state of the eye⁷, leading to temporary vision changes.

These changes can cause the lens to swell and then return to normal once blood sugar levels stabilize, which explains why your vision might be clear one day and blurry the next.

6. Hearing Impairment

Diabetes can affect so many parts of your body, and your ears are no exception.

High blood sugar levels can damage the blood vessels and nerves in your ears, which can lead to hearing problems.

Just like diabetes can cause damage to the nerves in your hands and feet, it can also impact the delicate structures in your ears.

This can make it harder to hear clearly and can even lead to sudden hearing loss.

A study published in the Annals of Internal Medicine found that hearing impairment is more common in adults with diabetes than in those without.⁸

The researchers suggest that high blood sugar levels can damage the small blood vessels and nerves in the inner ear, leading to hearing loss.

Therefore, if you’re noticing changes in your hearing, it’s a good idea to get your blood sugar levels checked. It could be a sign that your diabetes needs better management, and addressing it could help prevent further damage.

7. Gum Disease and Oral Health Problems

Red, swollen, or bleeding gums?

It might not just be a dental hygiene issue—it could actually be linked to your blood sugar levels.

When your blood sugar is high, it can weaken your immune system, which makes your gums more susceptible to infections. This can lead to gum disease and other oral health problems.

High blood sugar provides a perfect environment for bacteria to thrive, which can lead to infections in your mouth.

Your immune system is already working harder to manage your blood sugar, so it has less capacity to fight off these bacteria. This is why people with diabetes are more prone to gum disease.

A study published in the Journal of Periodontology found that individuals with poorly controlled diabetes are significantly more likely to develop periodontal disease than those with well-controlled diabetes.⁹

This is because high blood sugar levels can lead to inflammation and infection in the gums, making them more prone to bleeding and swelling.

8. Unusual or Fruity-Smelling Breath

This unusual or fruity-smelling breath is often a warning sign of diabetic ketoacidosis (DKA).

DKA happens when your body can’t use sugar for energy because of a lack of insulin, so it starts breaking down fats instead.

This process produces ketones, which can cause your breath to smell sweet or fruity.

When your body is running out of fuel, it turns to an alternative source—fat. But while this might sound efficient, it’s actually dangerous.

High levels of ketones in your blood can make it acidic, leading to severe health complications.

A study published in the Journal of Clinical Endocrinology & Metabolism found that people with DKA had elevated levels of ketones in their blood¹⁰, which corresponded with the characteristic sweet breath odor.

Therefore, if you or someone you know has diabetes and notices this unusual breath smell, it’s crucial to seek medical attention right away. It’s your body’s way of signaling that it needs help, and catching it early can prevent serious complications.

9. Extreme Hunger

Have you ever felt constantly hungry, no matter how much you eat? Like you just finished a meal, but your stomach is already growling again?

This persistent and excessive hunger can actually be a sign that your blood sugar levels are out of balance.

When you have diabetes, your cells can have trouble getting the glucose they need for energy.

Even though there’s plenty of sugar in your blood, it can’t get into the cells without enough insulin. So, your body responds by making you feel hungry, trying to get more energy.

It’s like your cells are starving in the middle of a feast.

They need glucose to function, but without insulin to help move the glucose into the cells, they can’t access it.

A study published in the Journal of Clinical Investigation found that individuals with insulin resistance—a hallmark of type 2 diabetes—experience increased hunger and food intake because their cells aren’t effectively absorbing glucose.¹¹

This leads to a vicious cycle of eating more but still feeling hungry because the cells remain deprived of the energy they need.

10. Unexplained Weight Loss

Are you losing weight without even trying?

While it might sound like a dream come true for some, unexplained weight loss can actually be a sign of something serious, especially if you have diabetes.

In type 1 diabetes, your body can’t produce enough insulin to help glucose get into your cells. Without this vital energy source, your body starts breaking down muscle and fat for energy instead, which leads to weight loss.

Imagine your body is like a car that suddenly can’t get gas, so it starts using up its own parts to keep running.

This process is your body’s desperate attempt to find fuel, which results in significant weight loss.

A study published in the American Journal of Clinical Nutrition found that people with type 1 diabetes who had poor insulin control experienced significant weight loss because their bodies were unable to use glucose effectively.¹²

Instead, their bodies broke down muscle and fat to compensate for the lack of accessible energy.

11. Frequent Urinary Tract Infections (UTIs)

When your blood sugar is elevated, it creates a prime environment for bacteria to thrive, which increases your risk of infections like UTIs.

Here’s how it works: sugar in your urine can essentially feed bacteria, making it easier for them to multiply and cause infections in your urinary tract.

In fact, a study published in the Journal of Clinical Microbiology found that individuals with poorly controlled diabetes are more susceptible to UTIs due to elevated glucose levels in urine.¹³

This higher urine glucose levels can promote bacterial growth, leading to recurrent UTIs.

So, if you’re experiencing these symptoms—like a strong urge to urinate, burning sensation, or cloudy urine—it might be worth checking your blood sugar levels.

Managing your diabetes effectively can help reduce your risk of UTIs and improve your overall urinary health.

12. Digestive Issues

Are you feeling full quickly or having frequent nausea and vomiting?

It might not just be something you ate—it could actually be related to your blood sugar levels, especially if you have diabetes.

High blood sugar can damage the nerves that control digestion, particularly the vagus nerve, leading to conditions like gastroparesis.

The vagus nerve helps regulate the movement of food through your digestive tract. When it’s damaged by high blood sugar levels, your stomach can’t empty properly, causing food to stay in your stomach longer than it should.

This delay in digestion can lead to symptoms like bloating, heartburn, and even episodes of vomiting.

Research published in the Journal of Diabetes and its Complications has shown that individuals with diabetes are at higher risk of developing gastroparesis due to nerve damage caused by chronic high blood sugar levels.¹⁴

While these symptoms don’t necessarily indicate diabetes, it’s crucial to consult with a healthcare provider for a comprehensive evaluation and appropriate testing.

Early detection and management can also help prevent complications and improve overall health.

How to Support Healthy Blood Sugar Levels

Maintaining healthy blood sugar levels is essential for overall health and well-being, especially for those with diabetes or at risk of developing it.

Here are key strategies to achieve and sustain healthy blood sugar levels:

Balanced Diet

When it comes to supporting healthy blood sugar levels, your diet plays a crucial role.

It’s not just about what you eat, but how you balance your meals.

A balanced diet should include a variety of foods: think vegetables, fruits, whole grains, lean proteins, and healthy fats.

These whole, unprocessed foods provide a steady supply of nutrients without causing rapid spikes in blood sugar levels.

Complex carbs, found in whole grains like brown rice and oats, legumes like beans and lentils, and vegetables like sweet potatoes and spinach, are digested more slowly.

This gradual digestion leads to a more gradual increase in blood sugar levels¹⁵, helping to maintain stability throughout the day.

Monitoring portion sizes is also key. Eating smaller, balanced meals and snacks throughout the day can prevent large swings in blood sugar levels.

This approach not only supports stable energy levels but also helps in managing weight—a crucial factor in blood sugar regulation.

High-fiber foods are another ally in this journey. Fruits, vegetables, and whole grains are rich in fiber, which slows down the digestion and absorption of carbohydrates.

This slow release of glucose into the bloodstream helps maintain more consistent blood sugar levels over time.

By incorporating these dietary principles—variety, complex carbohydrates, portion control, and fiber—you can take proactive steps to support healthy blood sugar levels and overall well-being.

Stay Hydrated

Staying hydrated is so important for keeping your blood sugar levels in check.

When you drink enough water, your body functions more efficiently, including how it handles glucose.

Dehydration, on the other hand, can lead to higher blood sugar levels because your body produces less urine.

This reduction in urine production makes it harder for your body to eliminate excess glucose, contributing to spikes in blood sugar.

Research published in the Diabetes Care journal shows that adequate hydration can help regulate blood glucose levels and improve insulin sensitivity¹⁶, making it easier for your body to use glucose for energy rather than letting it accumulate in the bloodstream.

To support healthy blood sugar levels, it’s essential to limit your intake of sugary drinks.

Beverages like soda, energy drinks, and sweetened coffees can cause rapid spikes in blood sugar due to their high sugar content.

Instead, opt for water, herbal teas, or other low-calorie beverages that won’t cause your blood sugar to skyrocket.

By staying hydrated with the right fluids, you can play an active role in maintaining stable blood sugar levels and supporting your overall health.

Regular Exercise

If you’re looking to support healthy blood sugar levels, regular exercise can make a big difference.

It’s not just about staying fit—it actually helps your body manage glucose more effectively.

When you exercise regularly, like with aerobic activities such as walking or cycling, or strength training like lifting weights, your muscles become more sensitive to insulin.

This means they can absorb glucose from your bloodstream more efficiently, which helps lower your blood sugar levels naturally.

A study published in the Journal of Clinical Endocrinology & Metabolism reports that physical activity enhances the body’s ability to use insulin effectively¹⁷, reducing the risk of high blood sugar levels.

Moreover, exercise directly lowers blood sugar levels by causing muscles to take up glucose for energy.

This action not only helps to bring down immediate blood sugar spikes but also supports overall blood sugar regulation over time.

To get the most out of your exercise routine, aim for at least 150 minutes of moderate-intensity aerobic activity each week.

This could include brisk walking, swimming, or dancing.

Additionally, incorporating muscle-strengthening activities like weightlifting or resistance exercises on two or more days a week can further enhance your blood sugar management.

By making regular exercise a part of your lifestyle, you can support healthy blood sugar levels and improve your overall well-being.

Manage Stress

Managing stress is crucial for keeping your blood sugar levels in a healthy range.

When you’re stressed, your body releases hormones like cortisol and adrenaline, which can cause blood sugar to rise.

To counter this, practicing relaxation techniques such as meditation, yoga, or deep breathing exercises can be really effective.

These activities help calm your mind and body, reducing the production of stress hormones that can spike your blood sugar levels.

A study from Psychoneuroendocrinology Journal reported that activities like mindfulness meditation and yoga can lower cortisol levels and enhance insulin sensitivity¹⁸, helping to stabilize blood sugar levels in individuals with diabetes.

Additionally, maintaining a positive outlook and engaging in enjoyable activities can further reduce stress and its impact on blood sugar regulation.

By incorporating these stress management strategies into your daily routine, you can support healthier blood sugar levels and overall well-being.

Taking time for relaxation and positivity isn’t just good for your mental health—it’s also an important part of managing diabetes and maintaining optimal blood sugar control.

Prioritize Good Sleep Hygiene

Getting quality sleep is crucial for keeping your blood sugar levels stable and supporting overall health.

Aim for 7-9 hours of sleep each night to help your body regulate insulin and glucose more effectively.

Studies, such as those published in Diabetes Care, have shown that inadequate sleep can lead to increased insulin resistance and higher blood sugar levels¹⁹, especially in individuals with diabetes.

Establishing a regular sleep schedule is also key.

Going to bed and waking up at the same time each day helps maintain your body’s internal clock, which plays a role in hormone regulation, including those that affect blood sugar.

Research also suggests that irregular sleep patterns can disrupt circadian rhythms, leading to fluctuations in insulin sensitivity and glucose metabolism.

Creating a restful sleep environment can further support healthy blood sugar levels.

Make sure your bedroom is conducive to sleep by keeping it cool, dark, and quiet.

Limiting exposure to screens and blue light from electronic devices before bedtime can also improve sleep quality.

These practices help promote relaxation and signal to your body that it’s time to wind down and prepare for restorative sleep.

By prioritizing good sleep hygiene—like aiming for consistent sleep hours, optimizing your sleep environment, and minimizing disruptions—you can help manage your blood sugar levels more effectively and improve your overall well-being.

Optimize Your NAD Levels

When it comes to supporting healthy blood sugar levels, optimizing your NAD (Nicotinamide Adenine Dinucleotide) levels can be a game-changer.

NAD is a vital coenzyme involved in energy metabolism and cellular function throughout the body.

In fact, a study published in the Cell Metabolism discovered that NAD plays a crucial role in improving insulin sensitivity, enhancing mitochondrial function, and reducing oxidative stress²⁰—all of which are key factors in maintaining stable blood sugar levels.

To naturally boost your NAD levels, incorporate habits like regular exercise and a balanced diet rich in NAD precursors.

Foods like fish, chicken, and avocados are high in niacin, a nutrient that supports NAD production.

Additionally, taking supplements that contain NAD precursors, such as nicotinamide riboside or nicotinamide mononucleotide, may be beneficial under the guidance of a healthcare provider.

How Optimizing NAD Levels Can Help Maintain Healthy Blood Sugar

NAD (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of the body, playing a vital role in various metabolic processes, including the regulation of blood sugar levels.

Here are several ways NAD can help maintain healthy blood sugar levels:

1. Improves Insulin Sensitivity

Optimizing your NAD levels can really make a difference in maintaining healthy blood sugar levels.

NAD is crucial for the activity of sirtuins, a group of proteins known for their role in regulating metabolic processes.

²¹Studies, such as those published in Cell Metabolism, highlight how sirtuins enhance insulin sensitivity—meaning they help cells respond better to insulin, allowing them to absorb glucose more efficiently.

This improved insulin sensitivity can lead to lower blood sugar levels and better overall glucose control.

2. Enhances Mitochondrial Function

Mitochondria are like the powerhouses of our cells, responsible for generating energy that fuels various metabolic processes, including glucose metabolism.

Research published in the Trends in Endocrinology & Metabolism, discovered that NAD is essential for the activity of enzymes involved in mitochondrial energy production.²²

By ensuring adequate NAD levels, you can help support the optimal functioning of mitochondria, which in turn enhances overall metabolism.

This improved mitochondrial function enables the body to efficiently utilize glucose for energy, thereby contributing to better blood sugar regulation.

3. Supports Glucose Metabolism

NAD is essential for glucose metabolism through its involvement in glycolysis and the Krebs cycle²³, as discussed in Cell Metabolism and Nature Reviews Molecular Cell Biology.

These processes are fundamental for converting glucose into usable energy within our cells.

NAD also acts as a coenzyme for key enzymes involved in glycolysis, where glucose is broken down to produce energy-rich molecules.

Additionally, NAD is crucial for the Krebs cycle, also known as the citric acid cycle, which further extracts energy from these molecules.

By supporting these metabolic pathways, NAD ensures that glucose is efficiently utilized for energy production rather than accumulating in the bloodstream.

4. Reduces Oxidative Stress

When blood sugar levels are high, it can lead to oxidative stress—a condition where there’s an imbalance between free radicals and antioxidants in the body, resulting in damage to cells and tissues.

Studies published in the Journal of Frontiers in Endocrinology and Journal of Diabetes Research emphasize NAD’s role in activating antioxidant enzymes like SIRT1 and catalase²⁴, which help combat oxidative stress and protect cells from damage.

NAD acts as a cofactor for these antioxidant enzymes, enhancing their activity to neutralize harmful free radicals generated during high blood sugar conditions.

By reducing oxidative stress, NAD helps maintain the integrity of cells and tissues, mitigating the detrimental effects associated with chronic hyperglycemia, such as diabetic complications.

Research also suggests that supporting NAD levels through dietary sources rich in NAD precursors (like niacin), regular physical activity, and potentially NAD-boosting supplements under medical guidance can enhance antioxidant defense mechanisms.

This, in turn, supports overall cellular health and contributes to better management of blood sugar levels.

By reducing oxidative stress, NAD plays a pivotal role in promoting long-term metabolic health and protecting against diabetes-related complications.

5. Promotes Healthy Inflammatory Response

Optimizing your NAD levels can really help maintain healthy blood sugar levels by promoting a healthy inflammatory response.

When inflammation becomes chronic, it can interfere with insulin signaling, which is crucial for cells to absorb glucose effectively.

According to a study published in the Journal of Immunology, NAD plays a vital role in regulating inflammatory pathways.²⁵

It acts as a cofactor for enzymes like SIRT1 and PARPs, which are involved in modulating inflammation.

By supporting these enzymes, NAD helps to balance the body’s inflammatory response, preventing it from becoming excessive or prolonged.

This balanced inflammatory state is essential for maintaining normal insulin function and ensuring that cells respond properly to insulin signals, thereby helping to keep blood sugar levels stable.

6. Aids in DNA Repair

NAD is crucial for the activity of enzymes involved in DNA repair. Maintaining genomic stability is essential for the overall health of metabolic pathways, including those involved in blood sugar regulation.

NAD is essential for the activity of enzymes like PARPs (Poly ADP-ribose polymerases) and SIRT1 (Sirtuin 1), which play critical roles in repairing damaged DNA.

DNA damage can occur due to various factors, including oxidative stress and metabolic dysfunction, which are often associated with high blood sugar levels.

By facilitating DNA repair processes, NAD helps to preserve the integrity of genetic material within cells.

This is crucial for ensuring that metabolic pathways, including those responsible for glucose metabolism and insulin sensitivity, function optimally.

However, NAD depletion or imbalance can impair DNA repair mechanisms, potentially leading to genomic instability and contributing to metabolic disorders such as diabetes.

Therefore, maintaining adequate NAD levels through dietary intake of NAD precursors (like niacin-rich foods), regular physical activity, and potentially NAD-boosting supplements may help support these repair processes and promote overall metabolic health.²⁶

7. Supports Weight Management

NAD is crucial for metabolic processes that regulate energy metabolism and cellular function.

When your body has sufficient NAD, it enhances mitochondrial function and promotes efficient energy production.

This can lead to better metabolism of fats and carbohydrates, which are key for maintaining a healthy weight.

NAD also plays a significant role in regulating adipose tissue metabolism and energy homeostasis,²⁷ contributing to overall weight management.

Furthermore, maintaining a healthy weight is closely tied to better blood sugar control.

Excess weight, especially visceral fat around organs, can lead to insulin resistance and higher blood sugar levels.

By supporting metabolic processes through optimal NAD levels, you can improve energy expenditure and enhance your body’s ability to manage blood sugar effectively.

If you want to support healthy blood sugar levels and reduce the risk of diabetes, it’s crucial to maintain a healthy diet, exercise regularly, and consider taking NAD supplements to optimize your metabolism and overall health.

How can you do it? Here are two ways:

Two Steps to Support Healthy Blood Sugar Levels

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