Author: Jinfiniti Science

How to Increase NAD+ Levels Naturally

Written by Jinfiniti Science on October 22, 2024. Posted in NAD, NAD+. No Comments on How to Increase NAD+ Levels Naturally

While its name may be complex, its importance to human health is crystal clear.

NAD+ (nicotinamide adenine dinucleotide) is one of the most important molecules in your body, present in every living cell. This remarkable compound stands at the center of cellular health, driving the fundamental processes that keep you alive and thriving.

Unfortunately, our NAD+ levels follow a predictable pattern – they steadily decline as we get older. This decline isn’t just a number on a chart; it’s one of the key reasons our bodies show signs of aging.

When NAD+ drops, it’s like having fewer batteries to power our cellular devices, leading to slower repairs and decreased efficiency throughout the body.

There is, however, a silver lining: science has revealed several natural ways to maintain healthy NAD+ levels.

Understanding and supporting your body’s NAD+ production can help your cells stay energized and resilient – essentially giving them the tools they need to function at their best.

In this article, we discuss…

The indispensable role NAD+ plays in supporting health and longevity
Factors beyond aging that contribute to the decline in NAD+ levels
Natural strategies to optimize your NAD+ levels
The single most effective way to increase NAD+ alongside a healthy diet, exercise, and proper nutrition

Understanding the Importance of NAD+

NAD+ is a fundamental molecule present in all living cells that serve as a critical link in cellular metabolism. This coenzyme plays a dual role: it facilitates the conversion of nutrients into cellular energy and acts as an essential signaling molecule in various biological processes¹.

At the cellular level, NAD+ is integral to energy production within mitochondria², where it helps convert carbohydrates, fats, and proteins into adenosine triphosphate (ATP) – the universal energy currency of cells.

Beyond energy metabolism, NAD+ is fundamental for maintaining genomic stability through DNA repair mechanisms³ and regulating inflammatory responses.

The significance of NAD+ becomes particularly apparent as its levels naturally decline with age. This decrease correlates with several physiological changes: reduced energy production, diminished cellular repair capacity, and altered metabolic function.

Research has linked insufficient NAD+ levels to various age-related conditions⁴, including metabolic disorders, neurodegenerative diseases, and compromised immune function⁵.

The cellular consequences of NAD+ decline manifest in observable effects on health and vitality. When NAD+ levels are adequate, cells maintain optimal energy production and repair capabilities.

Conversely, decreased NAD+ availability can lead to reduced metabolic efficiency⁶ and compromised cellular maintenance, potentially accelerating age-related cellular deterioration.

To put it concisely, having optimized NAD+ levels can support anti-aging efforts, reduce inflammation, and sustain energy levels throughout life.

The Causes of NAD+ Decline

Aging is one of the biggest factors behind the decline in NAD levels⁷, resulting from a series of interconnected biological mechanisms

For instance, DNA damage triggers enzymes like PARPs to repair cells⁸, consuming NAD+ in the process. Additionally, age-related inflammation (inflammaging) activates NAD-depleting enzymes like CD38⁹, which break down NAD+ during immune responses.

Mitochondrial dysfunction also worsens with age¹⁰, demanding more NAD+ to maintain energy production. Simultaneously, the efficiency of NAD+ synthesis declines as key enzymes, such as NAMPT, become less effective¹¹.

Furthermore, oxidative stress and the accumulation of senescent cells¹², which consume NAD+ and drive chronic inflammation, exacerbate this decline. Reduced NAD+ availability impairs the function of sirtuins, proteins vital for aging and metabolic regulation, creating a feedback loop that accelerates NAD+ depletion.

All these factors contribute to the age-related decline in NAD+ levels, impacting cellular health and energy production.

Aside from aging, excessive exposure to UV rays can also damage cells and speed up NAD+ depletion¹³. UV radiation triggers oxidative stress, which not only reduces NAD+ levels but also weakens the body’s ability to repair itself.

Drinking alcohol can also interfere with the body’s ability to maintain healthy NAD+ levels¹⁴. This is because the liver uses up a large amount of NAD+ to detoxify alcohol, which leaves less of it for other important functions around the body.

Chronic inflammation, whether from conditions like arthritis or autoimmune disorders, also accelerates NAD+ decline¹⁵. Inflammation causes oxidative stress, which depletes NAD+ and compromises its role in repairing damaged cells.

Natural Ways to Boost NAD Levels

If you’re feeling fatigued, recovering more slowly, or noticing other signs of NAD+ deficiency, you may be looking for ways to increase NAD levels naturally. Combining lifestyle adjustments with evidence-based approaches that support NAD+ production will help you increase your energy, enhance recovery, and improve your overall health.

Dietary Approaches

Your food choices play a role in maintaining healthy NAD levels.

Eating foods rich in NAD+ precursors¹⁶, like vitamin B3 (niacin), tryptophan, and fermented foods, can help support NAD+ production. These foods help by providing your body with the essential building blocks to synthesize NAD+.

Niacin, found in foods like turkey, chicken, and fish, can offer a helping hand in NAD+ synthesis. Tryptophan, present in eggs, nuts, whole grains, cow’s milk, and dairy, is another nutrient that can be converted into niacin, further increasing your levels of NAD.

Fermented foods like kimchi, sauerkraut, and kombucha promote gut health, which can indirectly support NAD+ production. Fermented foods contain very small amounts of NAD+ as a byproduct of the fermentation process.

Moreover, eating healthy fats from sources like avocados, olive oil, and fatty fish provides the nutrients needed to support cellular function and energy production, helping to support your NAD+ levels naturally.

Exercise and Physical Activity

Regular exercise protects against the decline in skeletal muscle NAD content associated with aging¹⁷.

Physical activity not only helps maintain NAD+ but contributes to regulating oxidative stress¹⁸, which is vital for maintaining energy levels and overall cellular health.

Aerobic exercise, such as running, cycling, or swimming, increases oxygen flow to your cells, promoting mitochondrial function and reversing age‐dependent decline in NAD+ salvage capacity¹⁹.

Interval training, where you alternate between high-intensity bursts and low-intensity recovery, has also been shown to increase the levels of NAD by enhancing metabolic processes efficiency and stimulating sirtuins—proteins that depend on NAD+ for cellular health²⁰.

Lifestyle Changes

Lifestyle changes, such as calorie restriction, intermittent fasting, and managing stress, can also help regulate NAD levels.²¹

Calorie restriction and intermittent fasting promote a process called autophagy²², which helps the body clear out damaged cells and regenerate new ones, helping stimulate NAD+ production and supporting cellular repair.

Additionally, adopting a ketogenic diet, which is high in healthy fats and low in carbohydrates, can help improve metabolic efficiency, further promoting NAD+ synthesis.

Stress management techniques such as meditation, yoga, and deep breathing also help reduce oxidative stress²³, which can otherwise deplete NAD+ levels.

Finally, getting quality sleep can help maintain healthy NAD+ levels. During deep sleep, the body undergoes restorative processes that require NAD+ to function optimally²⁴, including the activation of sirtuins.

Poor sleep or insufficient rest disrupts these processes, leading to increased oxidative stress and inflammation, which deplete NAD+ levels over time.

Restful sleep also helps regulate the circadian rhythm, which influences NAD+ metabolism²⁵. Maintaining a regular sleep schedule is therefore important for sustaining healthy NAD+ levels.

Heat Exposure

When the body is exposed to heat, it activates a response known as heat shock, which triggers the production of heat shock proteins that assist in repairing damaged cells and maintaining cellular health. This process induces an increase²⁶ in the NAD+/NADH ratio.

Regular use of saunas or hot baths has also been linked to increased longevity, improved circulation, and better mitochondrial function, all of which are important for maintaining healthy NAD+ levels.

Additionally, heat promotes better circulation by causing blood vessels to dilate, improving the delivery of oxygen and nutrients, including NAD+ precursors, to cells. This enhanced blood flow supports cellular energy and repair.

Regular sauna use has been shown to reduce inflammation, a major factor in aging, which helps prevent the depletion of NAD+ by reducing the activity of enzymes that break it down.

Together, these factors—improved circulation, mitochondrial function, reduced inflammation, and enhanced cellular repair—contribute to sustaining healthy NAD+ levels, supporting longevity and cellular health.

Supplements to Increase NAD Levels

To effectively boost NAD levels naturally, evidence-based supplementation should be paired with the key lifestyle changes outlined above. Research shows that targeted NAD supplementation, when paired with healthy daily habits, can address low levels of NAD and support your overall metabolic health.

Oral NAD+ supplements are one of the most popular and accessible ways to boost NAD+ levels. These often come in the form of sublingual NAD powder or capsules that contain NAD precursors, which are clinically proven to increase intracellular NAD levels.

NAD precursors include D-Ribose and Nicotinamide, which work synergistically to raise NAD levels.

Nicotinamide, a form of vitamin B3, serves as a direct precursor to NAD+ through the salvage pathway²⁷. It is converted to nicotinamide mononucleotide (NMN) by the enzyme nicotinamide phosphoribosyltransferase (NAMPT), and then to NAD+ by nicotinamide mononucleotide adenylyltransferases (NMNATs)²⁸.

D-Ribose enhances this process by stimulating NADPH production via the pentose phosphate pathway. NADPH is crucial for converting oxidized NAD+ back to its reduced form, NADH, thus maintaining the NAD+ pool. D-ribose may also improve the efficiency of nicotinamide utilization by providing the ribose sugar component needed for NAD+ synthesis.

Some supplements combine various NAD+ precursors like nicotinamide riboside (NR) with other compounds like resveratrol or pterostilbene, which may improve NAD+ metabolism or provide synergistic benefits.

Our Vitality ↑® NAD+ Booster is a clinically validated formulation consisting of NAD precursor, Creatine monohydrate, D-Ribose and Nicotinamide, four key compounds that work together to help maintain healthy levels of NAD+. While the effectiveness of NAD+ supplementation continues to be studied, each component in our formula has been individually researched for its role in cellular energy processes.

SHOP NAD+ BOOSTER

Advanced NAD Therapies

Advanced therapies for increasing NAD+ levels in the body include intravenous (IV) infusion and subcutaneous injection. Each method has distinct characteristics that influence its effectiveness and application.

NAD+ IV therapy delivers the compound directly into the bloodstream, bypassing the digestive system. This enables rapid uptake and immediate availability throughout the body’s tissues. Healthcare providers typically recommend this approach for addressing acute conditions like severe fatigue or for intensive therapeutic protocols.

Subcutaneous administration involves injecting NAD+ into the layer of tissue just beneath the skin. This creates a depot effect, where the compound is gradually released into circulation over an extended period.

These therapies require medical supervision and careful consideration of cost-benefit factors, including the price tag and potential side effects of NAD therapy. Medical screening and ongoing monitoring are essential, as these therapies may not be suitable for all individuals or medical conditions.

How to Monitor Your NAD Levels

Monitoring your NAD+ levels is important for understanding how well your body is maintaining energy and supporting cellular health.

The Intracellular NAD® Test measures NAD+ concentrations directly within cells, providing a precise assessment of your cellular NAD+ status. This measurement helps evaluate how lifestyle factors, dietary changes, and supplementation influence your cellular metabolism.

By establishing your baseline NAD+ levels before beginning any intervention, you can objectively track changes over time. Our research indicates that intracellular NAD+ concentrations of 40 micromoles (µM) or higher are associated with optimal cellular function. Regular monitoring enables evidence-based adjustments to supplementation protocols when needed.

Maintaining adequate NAD+ levels supports fundamental biological processes:

Mitochondrial energy production
Cellular stress response
DNA maintenance and repair
Metabolic regulation

While individual responses vary, optimizing NAD+ levels typically promotes cellular resilience and helps maintain metabolic function as you age. Regular testing provides actionable data to guide personalized interventions aimed at supporting cellular health.

TEST YOUR NAD LEVELS TODAY

Test Your NAD Levels with Jinfiniti

Is your NAD level where it should be?

Jinfiniti’s Intracellular NAD Test gives you an accurate measure of your NAD+ levels and shows how they impact your health.

Testing your NAD levels both before and after supplementation helps you find the right dosage for your body, as what works for one person may not be effective or could even be harmful to someone else.

With data from your NAD test, you can fine-tune your supplementation to get the maximum benefit and avoid over- or under-supplementing.

Jinfiniti’s NAD test gives you more than just numbers—it shows you what your body needs, helping you make better choices and optimize your health for improved vitality and longevity.

Referenced Sources:

NAD IV Therapy Side Effects: What are the Risks?

Written by Jinfiniti Science on October 18, 2024. Posted in NAD+. No Comments on NAD IV Therapy Side Effects: What are the Risks?

NAD IV therapy promises incredible results, from boosting energy to supporting anti-aging.

But is it too good to be true?

While the benefits sound great, there are common side effects of NAD therapy, from minor discomfort to serious complications, that you shouldn’t ignore.

Are the risks really worth it?

In this article, we’ll dive into:

The hidden safety concerns and side effects of NAD IV therapy that most people don’t talk about.
Critical factors you should consider before deciding if NAD IV therapy is right for you.
A safer alternative to NAD IV therapy that delivers results more efficiently without the downsides.

Recent studies show that by middle age, your NAD levels may drop to half of what they were in your youth¹. This decline can impact everything from your energy to how quickly you recover from stress.

It’s no surprise that NAD IV therapy has been gaining popularity as a quick fix for restoring vitality and slowing down the aging process. But with any growing trend comes important questions, particularly around safety.

Is NAD IV therapy as risk-free as it sounds? While the claims are exciting, it’s important to look at both sides, hence we’ll also dig into the risks and side effects in this article.

What is NAD IV Therapy?

Imagine having a “battery” in every cell of your body, constantly fueling your energy, repairing DNA, and keeping everything functioning smoothly. That’s the role of NAD (Nicotinamide Adenine Dinucleotide), a coenzyme essential for cellular health.

As we age, our NAD levels start to dip, leaving many of us feeling fatigued, recovering more slowly, and even noticing changes in our mental clarity.²

That’s where NAD supplementation comes into play, with many people turning to NAD IV therapy to help recharge those cellular “batteries.” NAD IV therapy involves infusing NAD directly into your bloodstream through an IV drip, bypassing the digestive system for quicker, more efficient absorption. The treatment typically lasts around four hours or longer, allowing the NAD to enter your body slowly while you relax.

Advocates of NAD IV swear by its benefits: increased energy, sharper focus, improved mood, and even anti-aging effects. Some even say it aids in addiction recovery, boosts athletic performance, and helps with cellular repair.

Common Safety Concerns of NAD Therapy

While many people report positive experiences with NAD IV treatment, there are some risks to consider, especially if the treatment isn’t administered properly, including:

Infection

Any time you’re dealing with an IV, there’s a risk of infection.³

Since the skin is punctured, bacteria can enter your bloodstream if the equipment isn’t properly sterilized. To reduce this risk, it’s important to have the treatment administered by trained professionals in a clean, medical setting.

Vein Irritation

Some people experience irritation or inflammation around the injection site.⁴

This could be due to the needle size, the frequency of treatments, or simply how your body reacts to the IV. While it’s usually minor and resolves on its own, it can still be uncomfortable.

Incorrect Dosage

Getting the dosage right with NAD IV therapy is crucial. Too little, and you may not experience the full benefits. Too much, and you could feel nauseous or dizzy.

A qualified practitioner will know the correct dosage for your body and specific needs.

Improper Administration

IV therapy requires precision. The placement of the IV, the dosage, and the flow rate all need to be exactly right.

If the person administering the treatment lacks experience, things can go wrong. You could end up with a poorly inserted IV or air bubbles in the line, which could lead to complications.⁵

Quality and Sourcing of NAD Products

Not all NAD products are created equal. The quality and purity of the NAD solution being used are vital to ensure you get the best results with minimal risk.

It’s important to choose a clinic that uses high-quality NAD sourced from reputable suppliers. If you’re given an inferior product, you could miss out on the benefits—or worse, face unwanted side effects.

What are the Side Effects of NAD IV Therapy?

Like any treatment, NAD IV therapy can come with its own set of side effects. While they’re usually mild, it’s important to be aware of what you might encounter during or after your session.

Common Short-Term Side Effects

Most people who try NAD IV therapy report mild side effects that tend to go away quickly. These can include nausea, flushing, and dizziness during or shortly after the treatment.

Some also report muscle cramping or chest tightness as the body adjusts to the NAD infusion. Though these milder symptoms typically fade after the session, they can be uncomfortable while they last.

Possible Long-Term Side Effects

While NAD IV therapy shows promise, there are concerns about its long-term effects, especially with frequent or high-dose intravenous treatments.

Flooding the body with excessive NAD, sometimes up to ten times the normal range, could disrupt its natural balance. This is a particular concern with unregulated IV bars, where dosage and frequency may not be carefully monitored.

While NAD+ is vital for various cellular processes, excessively high levels of NAD+ could potentially lead to adverse effects such as mitochondrial dysfunction or sirtuin overactivation.

NAD IV therapy has also been observed to cause a significant increase in high-sensitivity C-reactive protein (hs-CRP) levels in a substantial portion of recipients. Specifically, about 70% of individuals undergoing NAD IV therapy experience a 3- to 10-fold increase in hs-CRP, which is an acute phase reactive protein that indicates inflammation. To safeguard patient well-being, it is recommended to monitor hs-CRP levels and implement effective strategies to control inflammation.

If you are concerned about levels of inflammation, our at-home inflammation test kit, the AgingSOS® Senescence & NAD Panel, can help you reveal your inflammation status and take appropriate action.

AgingSOS® Senescence & NAD Panel

The Safest Approach to NAD IV Therapy

If you’re considering NAD IV therapy, safety should be your top priority. Here are a few key steps to ensure a safe and effective experience:

Choose a Qualified Provider

Your first step should be finding the right provider. Look for a licensed and experienced practitioner who specializes in NAD IV therapy.

Ask about their qualifications, experience with NAD treatments, and the safety protocols they follow. A reputable provider will gladly answer your questions and ensure you feel comfortable before moving forward.

Evaluate Your Health

Before starting any NAD IV therapy, it’s crucial to get a thorough health evaluation. Your provider should review your medical history, current medications, and any existing health conditions.

This helps determine whether NAD therapy is safe for you and allows them to tailor the treatment to your specific needs. Skipping this step could increase the risk of complications.

Monitor Your NAD Levels Regularly

To get the most out of NAD IV therapy and minimize risks, it’s also important to monitor your NAD levels.

The most effective way to do this is using an Intracellular NAD test, which measures the NAD levels within your cells. Keeping track of these levels during and after your sessions helps avoid issues like overdosing or underdosing.

This ongoing evaluation allows your practitioner to adjust your treatment for optimal results.

Test Your NAD Levels Today

Oral NAD Supplements: A Safer Alternative to NAD IV Treatment

While NAD IV therapy is popular for its quick delivery, it’s not the only option for boosting NAD levels. In fact, many people opt for an oral NAD+ supplement due to safety and convienience.

One big difference is how they work.

NAD IV therapy directly introduces the coenzyme into the bloodstream, but it is quickly metabolized and excreted, resulting in a short-lived effect.

Oral supplements, such as sublingual NAD powder, get absorbed by your cells and work from the inside out, helping to increase your body’s NAD+ levels gradually and sustainably. Plus, they’re much easier on the wallet and your schedule.

NAD IV can be both pricey and time-consuming, often costing hundreds per session and taking up to four hours or even more. In contrast, supplements are way more budget-friendly and easy to take, whether you’re at home or on the move. They fit right into your daily routine without any hassle.

Discover Our NAD Optimization® Supplements

Final Thoughts: Is NAD IV Therapy Safe?

NAD IV therapy has its benefits, but it’s not without risks. You might experience mild side effects like nausea or dizziness, or more serious issues like infections.

Safety is a big deal, especially if you’re thinking about using it long-term. It’s important to weigh these risks and talk to a qualified provider about whether it’s right for you. Take your time to weigh the pros and cons and find out if it suits your needs.

Also, don’t overlook safer alternatives like oral supplements. They work at the cellular level, naturally boosting NAD without the risks tied to IV treatments.

They also offer a more consistent, long-term boost, fueling your energy and overall health. Plus, you can take them anywhere, anytime, making them a hassle-free part of your daily routine.

So, if you’re seeking an effective, low-risk option to optimize your NAD levels and overall well-being, oral supplements may just be the better choice.

The best part? You can start today—without the needles or lengthy appointments.

Referenced Sources

NAD+ vs NADH: Differences Between the Two NAD Forms

Written by Jinfiniti Science on October 15, 2024. Posted in NAD, NAD+, Popular. No Comments on NAD+ vs NADH: Differences Between the Two NAD Forms

NAD, short for nicotinamide adenine dinucleotide, is a coenzyme important to the function of every cell in your body.

There are two forms of NAD: NAD+ and NADH.

Both NAD+ and NADH are important in energy production and other biological processes like DNA repair, metabolism, and cellular respiration, and they each have unique roles.

As we dive into the differences between NAD+ and NADH, you’ll find out how these molecular partners collaborate to maintain cellular equilibrium and support the myriad processes that sustain life at its most fundamental level.

In this article, we discuss:

The key differences between NAD and NADH, and why they matter for your health

How these molecules influence aging, energy production, and cellular communication

The impact of NAD+/NADH balance on your overall wellness and vitality

What form of supplementation is optimal to increase NAD+ and NADH

Are NAD and NADH the Same?

NAD+ and NADH are not exactly the same, but they are closely related forms of nicotinamide adenine dinucleotide (NAD).

NAD is essential for the proper functioning of every cell in the human body. It acts as a “helper molecule” that activates enzymes responsible for converting nutrients into usable energy. Without sufficient levels of NAD, cellular processes would grind to a halt, leading to various health issues.

NAD+ and NADH form a redox couple, meaning they are the oxidized and reduced forms of the same molecule, respectively. In a redox reaction, NAD+ loses an electron and becomes NADH, while NADH gains an electron and reverts to NAD+. This electron transfer is critical for energy creation and maintaining cellular redox balance.

So, what sets NAD+ and NADH apart? Let’s dive deeper into the unique roles of these fascinating molecules and explore how they work together to keep us alive and thriving.

Key Differences Between NAD and NADH

The key difference between NAD+ and NADH lies in their oxidation state¹:

NAD+ is the oxidized form, meaning it has lost electrons and carries a positive charge.
NADH is the reduced form, having gained electrons and carrying no charge.

This change occurs when a hydride (a hydrogen atom with an extra electron) binds to NAD+, turning it into NADH². This neutralizes NAD+ and alters its function in cellular processes.

In simple terms:

The NAD molecule acts as an electron acceptor, taking electrons during metabolic reactions.
The NADH molecule becomes an electron donor, passing electrons to another molecule.

This electron exchange is important for energy production and helps regulate metabolic balance. NAD+ is generally more abundant, making it a central player in redox reactions and supporting cellular communication.

Oxidation and Reduction

You may be wondering, how does NAD+ turn into NADH? It happens through oxidation and reduction.

In biochemistry, oxidation and reduction³ are processes where molecules transfer electrons, essential for energy production and maintaining balance in cells. Oxidation is when a molecule loses electrons, while reduction is when it gains electrons.

A clear example is NAD and its reduced form, NADH.

NAD+ is the oxidized form that accepts electrons, and when it gains electrons along with a hydrogen ion (H⁺), it becomes NADH, an electron donor. NADH then carries these electrons to critical cell processes, like the electron transport chain in the mitochondria, which produces ATP, the body’s main energy source.

This constant cycling between NAD+ vs NADH supports energy production.

During processes like glycolysis and the citric acid cycle, NAD+ is converted to NADH, storing energy. NADH then releases this energy by converting back to NAD+, which supports ATP production.

In summary, the switch between NAD+ and NADH is important for efficient energy management in cells, helping the body to function and maintain metabolic balance.

Chemical Structure and Properties

Nicotinamide adenine dinucleotide (NAD) is a coenzyme composed of two nucleotides connected by phosphate groups⁴, with one nucleotide containing an adenine base and the other a nicotinamide base.

The key structural difference between NAD’s oxidized form (NAD+) and its reduced form (NADH) is the presence of an extra hydrogen atom and two additional electrons in NADH. This modification neutralizes the positive charge on the nicotinamide ring of NAD+, changing its spatial configuration and interaction properties.

As a result, NAD+ acts as an electron acceptor, while NADH serves as an electron donor in redox reactions. The absorption and fluorescence properties of NAD+ and NADH are also important in their biochemical applications.

NAD+ absorbs light most effectively at 260 nm⁵ but does not exhibit fluorescence, making it undetectable by fluorescence-based assays. In contrast, NADH absorbs light at 340 nm and exhibits strong fluorescence when excited at wavelengths between 320-380 nm⁶, with emission occurring in the range of 420-480 nm.

This fluorescence property makes NADH highly detectable in biochemical experiments, particularly in metabolic studies. The ability of NADH to emit fluorescence when it is in its reduced form, and the significant change in fluorescence when it is oxidized to NAD+, provides an effective means for monitoring metabolic processes and redox balance in cells.

This non-invasive fluorescence measurement allows researchers to track cellular energy production and metabolic activity without the need for external dyes or labels, making it a powerful tool for understanding cellular health and metabolic states.

Biological Functions

NAD+ vs NADH are central to redox (reduction-oxidation) reactions, which are fundamental to cellular energy production.

In these reactions, NAD+ acts as an electron acceptor, becoming reduced to NADH by gaining electrons and a hydrogen ion (H⁺). This transformation is important for capturing the energy released during the breakdown of nutrients in processes like glycolysis and the citric acid cycle.

NADH, once formed, acts as an electron donor. It transfers high-energy electrons to the electron transport chain in mitochondria, where these electrons are used to generate ATP—the primary energy currency of cells.

The process of converting NADH to NAD+ during the electron transport chain helps power ATP synthesis, making this cycle crucial for producing cellular energy⁷.

Beyond its role in energy production, NAD and NADH are involved in various cellular signaling pathways, such as gene expression, DNA repair, and stress responses.

NAD+, in particular, interacts with enzymes like sirtuins and poly(ADP-ribose) polymerases (PARPs)⁸, influencing cellular activities that regulate metabolism, aging, and overall cellular health. For instance, sirtuins are a group of proteins that rely on NAD+ to perform their functions. This helps maintain metabolic balance, support healthy cellular processes, and regulate the cell’s response to oxidative stress⁹.

Without sufficient NAD+, sirtuins cannot function properly, leading to impaired cellular health and metabolic disturbances.

NAD+/NADH Ratio

The NAD+ to NADH ratio is a crucial marker of cellular health¹⁰, influencing a wide range of metabolic and biochemical processes. This ratio of NAD not only reflects the cell’s ability to produce energy but also plays a pivotal role in maintaining redox balance, DNA repair, and overall cellular function.

A higher NAD+/NADH ratio, which ranges from 3.1 to 3.6¹¹, is generally a sign of healthy cells, where NAD+, in its oxidized form, acts as a vital coenzyme in redox reactions. In these reactions, NAD+ facilitates the oxidation of nutrients, leading to the production of ATP, the cell’s primary energy source.

A balanced ratio ensures that the cell can efficiently generate energy and regulate vital processes, including maintaining DNA integrity and responding to oxidative stress. In contrast, when the ratio shifts toward higher NADH levels, the cell’s capacity for energy production is reduced, and oxidative stress increases¹². This imbalance often leads to diminished cellular function, making the cell more vulnerable to damage and disease.

The NAD+/NADH ratio also directly affects key metabolic processes. NAD+ plays a vital role in glycolysis, the citric acid cycle, and oxidative phosphorylation, all of which are essential for ATP synthesis. NADH, produced during these pathways, donates electrons to the electron transport chain in the mitochondria, ultimately driving the production of ATP.

A higher NAD+ concentration ensures that these metabolic processes run efficiently, while an imbalance, more NADH compared to NAD+, can disrupt cellular energy production and lead to metabolic dysfunction.

As people age, the NAD+/NADH ratio naturally declines. This decrease in NAD+ and the resulting increase in NADH levels are linked to reduced cellular energy production, impaired stress responses, and a decreased ability to repair cellular damage.

Age-related decline in NAD+ also contributes to the onset of chronic diseases, decreased physical resilience, and cognitive impairments. Additionally, the NAD+/NADH ratio is often disrupted in various diseases.

Conditions such as neurodegenerative disorders (e.g., Alzheimer’s and Parkinson’s disease), metabolic syndromes, and even cancer are frequently associated with an altered NAD+/NADH ratio¹³. These imbalances indicate impaired redox homeostasis and a compromised ability of cells to maintain proper function.

NAD+ and NADH in Aging and Disease

NAD+ is essential for maintaining cellular energy, but its levels naturally decline with age. This decrease in NAD+ impacts mitochondrial function, overall cellular health, and the development of age-related diseases.¹⁴

As we age, NAD+ levels drop across different tissues and cellular structures. This reduction impairs mitochondrial function by increasing the NADH/NAD+ ratio, leading to a higher concentration of NADH.

Elevated NADH promotes the production of reactive oxygen species (ROS), which contributes to oxidative stress.

The oxidative damage, coupled with diminished oxidative metabolism, results in decreased mitochondrial biogenesis and a breakdown of oxidative phosphorylation (OXPHOS)¹⁵. Consequently, cells begin relying more on glycolysis for energy, a less efficient pathway that often leads to metabolic issues.

An imbalance between NAD vs NADH can lead to many age-related diseases, including:

Metabolic Syndrome and Obesity: As NADH levels rise and NAD+ levels fall, mitochondrial function suffers, leading to insulin resistance¹⁶. This dysfunction can contribute to obesity, type 2 diabetes, and cardiovascular conditions. A key factor in this process is the reduction of nicotinamide phosphoribosyl transferase (NAMPT), an enzyme critical for NAD+ synthesis. In obesity, NAMPT activity decreases, exacerbating NAD+ depletion and impairing insulin sensitivity in various organs.
Cancer and the Warburg Effect: A shift toward glycolysis, known as the Warburg effect, occurs when mitochondria fail to produce sufficient energy¹⁷. This shift, often observed in cancer cells, involves increased glucose uptake and reliance on glycolysis, even in the presence of oxygen. This metabolic change links reduced NAD+ availability with cancer progression and other degenerative diseases.
Mitochondrial Dysfunction: Reduced NAD+ levels impair mitochondrial energy production, leading to conditions like mitochondrial myopathy, muscle weakness, and fatigue¹⁸. Research shows that restoring NAD+ levels with supplements, such as niacin, can improve mitochondrial function, increase muscle strength, and reduce fat, offering potential therapeutic benefits for those suffering from mitochondrial dysfunction.

The gradual depletion of NAD+ in our bodies over time fuels the onset of metabolic disorders, cancer, and mitochondrial diseases. This cellular energy decline acts as a catalyst for age-related health deterioration, underscoring NAD+’s pivotal role in maintaining our vitality and well-being as we grow older.

SHOP NAD+ BOOSTER

NAD+ and NADH in Energy Production

NAD+ and NADH are important in cellular energy production, particularly in processes like glycolysis, the citric acid cycle, and the electron transport chain, all of which contribute to ATP synthesis.

In glycolysis, which occurs in the cytoplasm, NAD+ picks up electrons and is reduced to NADH as glucose is broken down into pyruvate.¹⁹ This step is vital for the subsequent stages of energy production.

Next, in the citric acid cycle (also known as the Krebs cycle) within the mitochondria, NAD+ is again reduced to NADH as it helps process the products of glycolysis, releasing more electrons. These high-energy electrons are then carried by NADH to the electron transport chain, where they are transferred through a series of proteins in the mitochondrial membrane.

This transfer of electrons helps pump protons across the mitochondrial membrane, creating an electrochemical gradient that drives the production of ATP.

The entire process, from glycolysis to ATP synthesis, relies on the cycling between NAD vs NADH, ensuring that cells have a constant supply of energy to support all bodily functions.

NAD+ and NADH in Cellular Signaling

NAD+ is a regulator of various cellular signaling pathways²⁰, influencing key processes such as gene expression, DNA repair, mitochondrial function, and redox balance. It acts as a cofactor for a family of enzymes known as sirtuins, which regulate gene expression by modifying histones and other proteins involved in chromatin structure.

Sirtuins rely on NAD+ for their enzymatic activity, making NAD+ availability crucial for controlling genes related to aging, stress resistance, and metabolism.

Additionally, NAD+ is important in DNA repair by activating enzymes like PARPs (Poly ADP-Ribose Polymerases)²¹, which detect and repair DNA damage. A decline in NAD+ levels can impair the activity of these enzymes, leading to increased DNA damage and genomic instability over time—a hallmark of aging and disease.

Beyond its involvement in gene regulation and DNA repair, NAD+ is essential for mitochondrial function, as it fuels energy production pathways and supports mitochondrial biogenesis. Through its influence on sirtuins and other NAD+-dependent enzymes, it helps maintain mitochondrial health and efficiency, ensuring that cells can meet their energy demands.

Moreover, NAD+ helps maintain the redox balance within cells. The interconversion between NAD+ and its reduced form, NADH, is vital for redox reactions, enabling cells to respond to metabolic shifts and oxidative stress.

A proper NAD+/NADH ratio is necessary to preserve cellular homeostasis, prevent oxidative damage, and support the overall health and function of the cell.

Therefore, the availability of NAD+ is not only important for energy metabolism but also for the broader regulation of cellular health through multiple signaling pathways.

Measurement and Detection Methods

Maintaining optimal NAD+ levels is important for energy production, delaying age-related diseases, and supporting overall well-being.

With advancements in biological age testing, it’s now possible to measure NAD+ levels and assess the body’s oxidative stress, providing valuable information about metabolic health and the risk of conditions like diabetes, cardiovascular disease, and neurodegenerative disorders.

However, accurately measuring NAD+ and NADH levels presents challenges.

Traditional methods can be labor-intensive, sensitive to the stability of these molecules, and require complex sample preparation, which can affect their accuracy and reliability. Newer methods are available that provide more precise and reliable ways to measure NAD+ and NADH levels.

One example is the Intracellular NAD Test, which accurately measures your current NAD+ levels and determines whether they need optimization. These updated techniques help address the limitations of older methods, giving a clearer picture of your NAD+ status.

Additionally, testing your NAD+ levels is the only way to determine the optimal dosage for you. It’s important to measure both at baseline and after supplementation, as the same dosage may have different effects for different people—what works for one may be ineffective or even harmful for another.

Regular NAD testing provides data for more personalized health and NAD optimization.

NAD+ and NADH in Health and Wellness

NAD+ has become increasingly popular in health and wellness due to its benefits in energy production, DNA repair, and overall metabolic function. It therefore comes as no surprise that NAD+ supplements are drawing attention as potential interventions to support healthy aging and prevent age-related diseases.

As mentioned earlier, NAD+ levels decline with age, contributing to impaired cellular function and increased oxidative stress. Various forms of NAD+ precursors, such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), are available as dietary supplements and are being studied for their potential to increase NAD+ levels.

NAD+ supplementation has been investigated for its potential in treating neurodegenerative disorders, cardiovascular diseases, and metabolic conditions. Research has explored the use of NAD+ precursors in Alzheimer’s disease, where they may help reduce oxidative stress and improve cognitive function.²²

NAD+ therapies have been investigated for their potential to boost athletic performance and recovery by supporting cellular energy metabolism²³. The balance between NAD+ and NADH is also key in managing oxidative stress and inflammation, which are underlying factors in many chronic diseases. Some studies have explored the use of NAD+ supplementation in type 2 diabetes²⁴, where it may help improve insulin sensitivity and glucose metabolism.

In addition to supplements, NAD IV therapy through methods like infusions and transdermal patches has gained popularity for NAD+ replenishment. Users often report benefits like improved mental clarity, reduced fatigue, and enhanced athletic performance. However, it’s important to be aware of potential side effects and risks involved with IV therapy. High doses of NAD+ can cause symptoms like nausea, headaches, and digestive discomfort. Excessive NAD+ levels may also disrupt the body’s redox balance, potentially increasing oxidative stress under certain conditions.

As research progresses, it is likely that we will see further developments in NAD+ based therapies and a deeper understanding of how these molecules can be leveraged to promote health and combat age-related decline.

Is It Better to Supplement NAD+ or NADH?

Several human clinical trials²⁵ have demonstrated the safety and efficacy of NAD+ precursor supplementation. These studies have reported improvements in various health parameters²⁶, such as reduced inflammation, enhanced insulin sensitivity, and improved cardiovascular function. Additionally, NAD+ precursors have been associated with increased energy levels, improved cognitive function, and better sleep quality.

In contrast, supplementing with NAD+ or NADH directly may not be as effective due to its instability and lower bioavailability²⁷. NADH is rapidly oxidized to NAD+ in the body, making it challenging to maintain elevated levels through supplementation. Furthermore, the majority of studies investigating the benefits of NAD-related supplements have focused on NAD+ precursors rather than NADH²⁸.

Test Your NAD Levels with Jinfiniti

Is your NAD level where it should be?

Jinfiniti’s Intracellular NAD Test gives you an accurate measure of your NAD+ levels and shows how they impact your health.

With data from your NAD test, you can fine-tune your supplementation to get the maximum benefit and avoid over- or under-supplementing.

Jinfiniti’s NAD test gives you more than just numbers—it shows you what your body needs, helping you make better choices and optimize your health for improved vitality and longevity.

TEST YOUR NAD LEVELS TODAY

Referenced Sources:

Is Spending 4 Hours or More on NAD IV Therapy Really Worth Your Time?

Written by Jinfiniti Science on September 30, 2024. Posted in NAD, NAD+. No Comments on Is Spending 4 Hours or More on NAD IV Therapy Really Worth Your Time?

Can you really afford to block out four hours for one treatment and possibly return every 4-6 weeks for maintenance?

While NAD IV therapy offers impressive benefits, the time commitment might make you wonder if it’s truly worth the hours lost.

If you’re curious whether these benefits justify the long appointments or if there’s a more convenient option that better suits your lifestyle, keep reading to find out more.

In this article, we’ll dive into:

Why the 4-hour commitment is necessary and what makes it so time-consuming
The quick benefits of NAD IV therapy and how they stack up against the extended time requirement.
A more efficient alternative to NAD IV therapy that fits seamlessly into a busy lifestyle.

Imagine spending 4+ hours hooked up to an IV, just to boost your energy and mental clarity.

And let’s be honest — those hours aren’t exactly relaxing.

The waiting, the sitting still, and the constant drip can feel more stressful than rejuvenating.

That’s the reality for most people undergoing NAD IV therapy.

With busy schedules, tight deadlines, and never-ending to-do lists, is it really worth blocking off half your day for one session?

Or is there a more efficient alternative? Let’s take a closer look.

Why Does NAD IV Therapy Take 4 Hours or More?

NAD IV therapy, often referred to as NAD IV drip or NAD drip, is known for its extended sessions, typically lasting four hours or more.

But why does it take so long?

The primary reason lies in the slow infusion process required for optimal absorption.

NAD (nicotinamide adenine dinucleotide) is a crucial coenzyme involved in energy production and cellular repair¹.

To be effective, it needs to be administered slowly to ensure it’s properly absorbed by your body.

The slow drip allows your body to gradually assimilate the NAD, minimizing potential side effects, such as dizziness and inflammation, and maximizing its benefits.

This process, while beneficial, can be inconvenient for those with tight schedules.

Top Immediate Benefits After NAD IV Therapy

After spending hours hooked up to a NAD IV drip, what do you get out of it? Many people experience noticeable benefits right away, including…

Increased Energy

One of the biggest draws of NAD IV therapy is the immediate energy boost² that many people experience.

By replenishing your body’s NAD (nicotinamide adenine dinucleotide) levels, which naturally decline with age³, this therapy helps restore your cells’ ability to produce energy efficiently.

People often report feeling revitalized and much more energetic after a session.

Whether you’re dealing with burnout, or just looking for a quick energy lift, NAD IV therapy can leave you feeling more alive and ready to tackle your day.

Mental Clarity

Ever feel like your brain’s in a fog? NAD IV therapy might help clear that up.

One of its top cognitive benefits is enhanced mental clarity⁴ — sharper focus, quicker decision-making, and overall better brain function.

Since NAD is involved in mitochondrial function⁵ (the powerhouse of your cells), optimizing your NAD levels can have a direct effect on how well your brain performs.

Many people notice that after a session, their thoughts are more organized, and they can concentrate for longer periods.

For anyone who feels mentally sluggish or easily distracted, NAD IV therapy can provide that extra mental edge.

Better Mood

NAD IV therapy may help improve your mood by supporting neurotransmitter balance⁶.

According to a 2020 study published in the MDPI Journal, NAD plays a key role in the production of serotonin⁷, a chemical in the brain that regulates mood and stress levels.

As your body processes the NAD, you may experience a sense of calm and well-being.

People often describe feeling more relaxed, less anxious, and more emotionally balanced after therapy.

Improved Focus

If you find yourself struggling to stay on task or jumping from one thing to another, NAD IV therapy might help.

By boosting NAD levels, which are crucial for energy production in the brain⁸, the therapy can improve your ability to focus.

Many people report that after their session, they’re able to concentrate better and stay on top of their work or personal tasks without feeling mentally drained.

Whether you’re in a demanding job or juggling multiple responsibilities, better focus is a benefit that can make a real difference in your day-to-day life.

Is NAD IV Worth Four Hours of Your Time?

Committing four or more hours to a single NAD IV therapy session is a big ask, especially for those with packed schedules.

Between work, family, and personal time, carving out that much of your day can feel like a luxury few can afford.

The main inconvenience is, of course, the time commitment.

Sitting for hours while the IV slowly drips can be frustrating, especially if you’re someone who’s constantly on the go.

For busy individuals, this lengthy session can disrupt their entire day.

You might have to reschedule meetings, shift deadlines, or even cancel personal plans just to fit it in.

The question is, do the benefits justify such a commitment?

If you’re dealing with severe fatigue, mental fog, or health issues that other treatments haven’t resolved, NAD IV might be worth the investment.

But for many people, the idea of spending half a day tethered to an IV isn’t appealing.

You have to weigh whether these benefits are worth shaking up your busy schedule, especially when other options offer similar or even better results more conveniently.

Is There a More Efficient and Faster Alternative to NAD IV?

If the thought of sitting in a chair for four hours isn’t your idea of a good time, you’ll be happy to know there’s a more efficient option: oral NAD supplements like Vitality Boost.

These supplements offer many of the same benefits—enhanced energy, mental clarity, and better mood—without the hassle of IV therapy.

They typically contain NAD precursors⁹ like nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), which your body turns into NAD+.

While they might not give you the immediate energy boost that IV therapy does, they’re highly effective at working directly on a cellular level and supporting overall well-being.

Plus, they’re much more convenient and easier to fit into a busy lifestyle.

Instead of blocking out half your day for a therapy session, you can simply take a daily dose of an oral supplement — anywhere, anytime.

You can maintain your routine without needing to rearrange your life for a therapy appointment.

To get the most out of oral supplements like Vitality Boost, it’s best to pair them with a healthy diet and regular exercise.

A 2022 study by Australian scientists, published in Aging Cell Journal, found that just 20 minutes of cycling can boost NAD levels in young adults¹⁰.

So, combining these supplements with a balanced diet rich in NAD-boosting foods like fish and leafy greens and consistent physical activity can help you stay energized and focused.

SHOP NAD+ BOOSTER

Is NAD IV Therapy Worth It or Not?

So, is NAD IV therapy really worth the time investment?

The answer depends on your individual needs and lifestyle.

For some, especially those with conditions due to severe NAD depletion like chronic fatigue, the immediate benefits of NAD IV therapy can be a game-changer.

But for most people, especially those with busy lives, committing half a day to therapy sessions isn’t practical.

While NAD IV therapy delivers results quickly, the inconvenience of carving out that much time could outweigh the benefits.

That’s where more efficient alternatives, like oral NAD supplements, come in.

They offer many of the same perks like mental clarity and improved mood without the need for lengthy appointments.

Ultimately, whether or not NAD IV therapy is worth it comes down to your priorities.

If you’re after immediate, dramatic effects and can spare time, it might be a worthwhile investment.

But for most people, the convenience of oral NAD supplements offers a more practical solution without the time drain.

Before committing to NAD IV therapy, consider your lifestyle, health goals, and how much time you’re willing to invest.

You might find a more time-efficient option fits better with your daily routine, while still delivering the results you want.

SHOP NAD+ BOOSTER

Referenced Sources:

NAD IV Therapy Cost: How Much Should You Expect to Pay?

Written by Jinfiniti Science on September 24, 2024. Posted in NAD, NAD+, NAD+ Precursors, Popular.

Imagine unlocking boundless energy, razor-sharp focus, and a renewed sense of vitality—not through another fad diet or grueling workout, but by tapping into your body’s own cellular powerhouse.

This isn’t science fiction; it’s the promise of NAD IV therapy, a cutting-edge treatment that’s captivating health enthusiasts and Hollywood A-listers alike.

But as with any breakthrough, the question on everyone’s mind is: Does the price tag match the potential? Read on to discover all you need to know about the costs of NAD therapy and determine whether this cellular rejuvenation is truly worth your investment.

In this article, we discuss:

The science of NAD therapy and understand how it works to boost your energy and vitality.
What you should expect to pay for NAD IV treatment and discover if it’s the right choice for you.
How to enjoy celebrity-level energy and anti-aging benefits without the Hollywood price tag – all for just a fraction of the cost!

NAD IV therapy has quickly become the latest wellness trend, touted for its ability to boost energy, sharpen the mind, and even slow down the aging process.

Hollywood stars like Jennifer Aniston and Justin Bieber use this treatment to optimize their health. Podcaster Joe Rogan is also a fan, adding to the therapy’s growing appeal.

High-performing athletes are getting on board too, recognizing NAD+ IV therapy for its potential to enhance athletic performance and support recovery. In fact, former NFL quarterback Jay Cutler turned to NAD+ therapy after his 12-year career, where he suffered from 15 head injuries.

But before you jump on the bandwagon, it’s important to get a clear picture of the costs involved in ongoing NAD treatment and weigh them against the potential benefits.

What is NAD IV Therapy?

NAD IV therapy is a treatment designed to deliver a powerful coenzyme called nicotinamide adenine dinucleotide (NAD) directly into your bloodstream.

NAD is crucial for cellular energy, aiding in metabolic processes like DNA repair, combating oxidative stress, and regulating circadian rhythms.¹

A 2022 study published in the Frontiers in Endocrinology Journal reported that as you age, your NAD levels naturally decline.² This decline can contribute to various health issues like fatigue and cognitive problems.

The purpose of NAD IV therapy is to replenish these diminishing NAD+ levels quickly and efficiently.

NAD boosts your cells’ energy by enhancing the production of adenosine triphosphate (ATP), the primary fuel that powers cellular function. It also activates a family of proteins called sirtuins, which help repair cellular damage, manage stress, and keep your metabolism in check.³

NAD IV therapy skips the digestive system, sending a concentrated dose of NAD straight into your bloodstream. This can lead to faster and more noticeable benefits. This is why many people report feeling more energized, mentally sharp, and physically resilient after undergoing NAD IV therapy.

How Much Does NAD IV Therapy Cost?

The cost of NAD IV therapy can vary widely, but on average, you can expect to pay anywhere from $500 to $2,000 per session. The exact price depends on several factors, including the clinic’s location and reputation.

In major cities like New York, Los Angeles, and Chicago, a single NAD IV session might range from $600 to $1,000 or more. These cities have a higher cost of living, and clinics often charge a premium for their services to cover expenses and cater to a wealthier clientele.

In contrast, smaller towns or rural areas offer more affordable options, ranging from $300 to $500. Lower costs in these areas often stem from reduced overhead, lower demand, and the need to attract customers with less disposable income compared to big cities.

Moreover, a clinic known for delivering high-quality results or one favored by celebrities and influencers may charge a premium for their services. These clinics often invest in state-of-the-art equipment, highly trained staff, and luxurious amenities, all of which contribute to higher costs.

The cost of NAD IV therapy is also influenced by the dosage and length of each session. Typically, higher doses of NAD+ require more time to administer, resulting in longer sessions and higher costs.

Additional Fees

Beyond the base cost, there are often additional fees to consider.

Many clinics charge for initial consultations, which can range from $100 to $200, depending on the provider. Follow-up consultations may also come with a fee, especially if your therapy is personalized and requires ongoing monitoring.

You may also face costs for add-ons like vitamin infusions or hydration boosters, which can enhance your therapy and address specific health needs. These extras can add another $50 to $200 per session.

If you’re traveling to a clinic far from home, you’ll need to factor in potential travel expenses. This might include transportation, accommodation, and meals, all of which can increase the overall cost of your treatment.

Cost of Multiple NAD Therapy Sessions

NAD IV therapy is often most effective when done over multiple sessions, especially for long-term benefits. As a result, the cumulative cost can add up quickly.

Typically, it’s suggested to start NAD+ IV therapy with weekly sessions for the first four weeks, followed by bi-weekly treatments for the next month. After that, you can often switch to just once a month to maintain the benefits.

If you’re considering a series of treatments, some clinics offer packages or discounts for multiple sessions. However, even with discounts, you might be looking at a total cost of several thousand dollars, particularly if you undergo therapy over several weeks or months.

Is NAD IV Therapy Covered by Insurance?

NAD IV treatment plans are not typically not covered by health insurance in the United States. Most insurance providers consider this treatment elective or alternative, placing it outside the scope of standard medical coverage.

The reason for this lack of coverage is twofold: NAD IV drip therapy is not FDA-approved for treating specific medical conditions and it’s often categorized as a wellness or anti-aging treatment rather than a medical necessity.

While insurance coverage for NAD IV therapy is unlikely, it’s always worth checking with your specific insurance provider. In rare cases, coverage may be possible if the treatment is deemed medically necessary for a diagnosed condition. However, such instances are the exception rather than the rule.

NAD IV Therapy vs Oral NAD Supplement Cost

If you’re aiming to boost your NAD+ levels, two popular choices are NAD IV therapy and oral NAD supplements.

NAD IV therapy is the pricier option, with monthly sessions adding up to around $6,000 a year.

In contrast, oral NAD supplements offer a practical choice, with a month’s supply ranging from $40 to $100. Over a year, you could spend as little as $480, making it a more sustainable way to support your NAD+ levels long-term.

But beyond the price, it’s far more important to consider how these methods work with your body. One key issue with NAD IV therapy is whether the NAD+ actually gets into your cells to boost your levels effectively.

NAD molecules are too big to pass through cell membranes, so most of the NAD+ ends up staying outside the cells. This means NAD IV therapy might not be as effective at raising intracellular NAD+ levels and providing the health benefits you’re looking for.

On the other hand, oral NAD supplements supply your body with the raw materials it needs to make NAD+ on its own. It’s a more efficient approach that directly supports the cellular processes that keep you energized, healthy, and resilient.

Is the Cost of NAD IV Therapy Worth It?

NAD IV therapy can be effective, but there’s a lot to consider.

Each session may take up to 4 hours, so you’ll need to set aside a big chunk of your time. Plus, since multiple sessions are often required, the time and effort can really add up. The speed of the infusion matters, too, as faster infusions are linked to side effects like stomach pain.

If you want to save on both cost and time, oral NAD supplements are a solid alternative.

You can take them whenever and wherever you want—no appointments or long waits.

They come in different forms like NAD powders and sublingual drops, so you can easily fit them into your daily routine.

However, not all NAD supplements are created equal.

Just like with NAD IV therapy, some supplements only contain NAD+ itself, which doesn’t always get into your cells effectively due to its limited bioavailability.

For best results, choose supplements with NAD+ precursors. They’re easier for your body to absorb and convert into NAD+ inside your cells.

SHOP NAD+ SOLUTIONS

Referenced Sources

True Story: Dementia-Related Memory Loss Restored 50% OVERNIGHT

Written by Jinfiniti Science on September 2, 2024. Posted in Memory Loss and Brain Fog, NAD, NAD+, Neurological Diseases, Popular. No Comments on True Story: Dementia-Related Memory Loss Restored 50% OVERNIGHT

Dementia is a serious condition that affects over 55 million people worldwide, with nearly 10 million new cases each year¹.

The impact of dementia goes far beyond the person who is diagnosed; it also deeply affects their families, who struggle with the emotional and mental pain of seeing their loved ones’ memories fade away.

Watching someone you care about lose the ability to do everyday things, forget important moments, or fail to recognize familiar faces can be incredibly hard.

Families often feel helpless and overwhelmed, desperately searching for ways to restore what has been lost.

But there is hope.

Take Marshall, a 94-year-old who completely forgot how to use his phone and computer after being diagnosed with dementia.

After just one night of using Vitality NAD+ Booster, a supplement that contains nicotinamide adenine dinucleotide (NAD) precursors, Marshall’s memory began to improve, and he started to feel more like himself again.

SHOP NAD+ BOOSTER

His story shows that it’s possible to regain lost memories and improve mental clarity.

We hope that you or your loved ones can also benefit from optimizing your NAD+ levels.

Read Marshall’s story below.

I’m not sure what I expected, but…

I was surprised when my dear friend’s cognition declined dramatically overnight at age 94.

Sure, there had been some memory lapses over the course of his 93^rd year.

He occasionally forgot his house keys when he went out. He didn’t always remember everything he had driven to the grocery store to buy. (Yes, he was still driving safely at age 92 and beyond.)

Those lapses were the kind that everyone I know over the age of 40 has complained about, myself included.

Still, the signs of Marshall’s cognitive decline did not progress over the course of weeks or months, as I had believed they would, were they to happen at all.

I had hoped that he was past some imaginary statistical cutoff date by which I had presumed dementia would happen. I had read somewhere that by the age of 80, 1 in 6 people experienced some degree of dementia.

When my dear friend reached and passed his 90^th birthday with a mind sharp as a tack I assumed he was all clear.

By the time he celebrated his 94^th birthday, I relished the fact that he remembered things better than many 40-year-olds and he still “figured stuff out” (his phrase) really well for a person of any age.

Give him a problem to solve and if he hadn’t done so by day’s end, he would always spring out of bed the next day declaring, “I’ve got it!” having solved the problem throughout the night.

Marshall’s great mind and good memory were perfectly intact until one fateful day.

That day I discovered him sitting on his bed staring quizzically at his phone.

I asked him, “What are you doing, M?” He looked at me, bewildered, and replied, “I don’t know.”

I pressed him further. “What do you mean, ‘You don’t know’? Are you trying to call someone on your phone?” I asked.

“I’m trying to figure that out,” he told me. “I’m working on it.”

His words weren’t making sense to me. Working on what? What did he mean?

“Marshall,” I began, worried, “What do you mean ‘working on it”? What’s to work on? Just make the call if that’s what you’re trying to do.”

He looked at me with a blank expression and replied, “I don’t know how.”

I flashed back to years earlier when a very beloved actor friend of mine had called me at my apartment in New York City. He was talking to me in disconnected, somewhat incoherent phrases that I couldn’t understand.

Clearly, something was wrong.

I asked him where he was and he somehow managed to tell me with words that made some sense that he was at the nearby Apple Store.

I told him to stay where he was, that I would be right over. I quickly threw on a jacket and ran the four blocks to the store.

I found my friend sitting at a display bench downstairs in the store with an Apple clerk who seemed concerned.

My friend was insisting that she sell him a new iPhone, which she explained to me she didn’t want to do because his current model phone was working just fine.

I told her to cancel the order, which she didn’t want to place anyway.

I asked him a few questions, which he answered only somewhat coherently.

I apologized to the salesgirl and walked my friend out of the store. I found a bench where he could sit comfortably while I called his family at their home.

They were understandably concerned when I told them about his condition.

They were in another state but together we made the decision that I should get him to the nearest Urgent Care.

The staff there quickly diagnosed a suspected stroke and, with their help, I hastily got my friend to a nearby hospital.

He spent a week in the hospital and recovered, but things could have gone in a whole other direction had I not jumped into action when I did.

Was Marshall suffering the effects of a stroke? I determined to keep a close eye on him throughout that entire day.

I observed him sitting and staring into space from time to time, as though lost in thought.

When I asked him what he was thinking about, he said, “I’m figuring something out,” and he would return to gazing off into the distance with a vacant stare.

Later that day I discovered him sitting at his computer, staring at the screen, immobile.

“What are you doing, Marshall?” I asked him.

“I don’t know. I can’t answer that,” he said, clearly frustrated and confounded.

From one day to the next my friend had forgotten how to use both his cellphone and his computer.

Worse, he seemed “not all there” mentally.

There’s more but I won’t go into the details, which included some bathroom and basic walking issues. Suffice it to say he had devolved significantly over just 24 hours.

Over the next weeks, I took my friend from doctor to specialist to lab to ascertain exactly what was going on.

A brain MRI (not fun for him at all) ruled out any suspected brain mass/tumor but…

A battery of cognitive tests with a gerontology professional confirmed that he was experiencing mild to moderate dementia.

Watching him take that cognition test was painful because questions that he would have aced just the week before gave him great difficulty in answering.

He couldn’t even begin to draw the clock face requested in the test.

A former whiz with numbers, he was stumped when asked to count back from 100 in 7’s. (100, 93, 86, etc.) His frustration turned to anger and eventually, he refused to participate in completing the test.

Once home, I was shocked to discover that Marshall had completely mixed up his daily meds.

As a forever health freak and gym rat, he had always been compliant and rigorous with taking vitamins and the few prescriptions he was on.

He had gone on his first prescription meds just a few years before when diagnosed with non-small-cell lung cancer.

He was doing ok with that disease, given his age and the severity of such a condition.

The health equity he had built up over decades of clean, healthy living stood him in good stead to do battle with cancer.

He never missed a prescribed dose of anything the oncologist ordered and his vitamin game was strong after years of taking a full regimen of fitness and bodybuilder supplements.

However, a review of his medicine cabinet that day showed that things had gone very awry.

Some bottles that I knew should be there were missing and others contained far too many pills than they should have since the date of fulfillment at the pharmacy.

When I asked him if he had been taking his pills regularly, as he had always done, he looked at me with that new vacant, uncomprehending stare.

I took possession of all bottles from his bathroom shelf and called all of his prescribing doctors to review his treatment plan and get him back on track.

I took over the administration of meds and supplements. I felt lucky to have discovered the issue when I did.

Fortunately, doing some math on the bottles and the number of pills inside them proved that the pill problem had occurred concurrently with the cellphone and computer problem. Suddenly and recently.

With a heavy heart, I booked tours of Assisted Living homes in advance of what I was sure would soon be the need for 24/7 memory care.

And then I had a thought.

What if Vitality NAD+ Booster, a NAD supplement formula and known neurotransmitter, could help?

It is a favorite of mine and so many others for energy mental clarity and more. Why not give it a try?

That night I gave Marshall his first dose of the clinically-proven powder. The next morning? Nothing short of a medical miracle.

I could kick myself for not having recorded the “before” Vitality NAD+ Booster Marshall to the man who woke up that next day.

When I claim a 50% improvement in his cognition OVERNIGHT it sounds preposterous even to me!

Except I witnessed it. I continue to see it daily.

Has he suddenly regained 100% of his memory and ability to solve problems and think clearly?

Most definitely not. He is, however…

At least 50-65% cognitively recovered.

He knows how to use his phone, he’s back at the computer, those bathroom issues are pretty much gone, and he’s using his walker and cane as well as he formerly had.

He is now back in charge of his meds and supplements because he began to remind me to give him doses as he remembered what to take and when.

I check daily to make sure he has not forgotten anything, of course, but so far, so good.

I do mix up his Vitality NAD+ Booster for him and give him two scoops daily.

When he sees me coming with it, his eyes light up and he says, “Dr. She’s stuff?” and I shake my head “yes” in acknowledgment.

I think he looks forward to it because he knows the good it does him.

During a doctor visit with his Primary Care Physician yesterday, the doctor acknowledged the improvement he saw in Marshall.

I told him what I had added to the program and he said, “Well great, there is good data on that supplement.”

He’s one of the physicians I had taken Marshall to see to evaluate the sudden mental decline.

He’s the same doctor who had told me back then several months ago that Marshall could not be left alone anymore.

“If he can’t use his phone and he gets in trouble, it’s a big problem,” he advised.

Plus, he mentioned the stove incident that had happened during that awful week:

Marshall had turned on a gas burner that didn’t light and some gas fumes escaped before I noticed what was happening.

I’m grateful for however many months, hopefully, even years, that this product will enable my dear friend to enjoy his mind and his memory.

If it stopped working tomorrow, I would still be grateful today for the past six weeks of improvement.

Dementia moves in and makes itself at home with all too many families today. It’s a significant global health challenge.

Here are some key statistics highlighting the fact that it’s not “if” it’s “when” a friend, neighbor, work colleague, or family member of yours may experience this heartbreaking condition:

Global Prevalence: As of 2023, more than 55 million people worldwide are living with dementia. This number is expected to nearly triple by 2050, reaching 139 million due to aging populations.

Incidence: Around 10 million new cases of dementia are diagnosed each year. That equates to one new case every 3 seconds.

Age Factor: Dementia primarily affects older adults. About 1 in 6 people over the age of 80 have dementia. However, early-onset dementia, which occurs before the age of 65, accounts for about 9% of cases.

Economic Impact: The global cost of dementia is estimated to be over $1 trillion annually, including healthcare costs, informal care, and loss of productivity. This figure is projected to increase significantly in the coming decades.
Mortality: Dementia is one of the leading causes of death worldwide. In many countries, it ranks as the second or third leading cause of death among older adults.

Gender Disparity: Women are disproportionately affected by dementia. Approximately two-thirds of people with dementia are women, partly because women tend to live longer than men.

Alzheimer’s Disease: Alzheimer’s disease is the most common form of dementia, accounting for 60-70% of all cases.

These statistics underscore the importance of research, prevention, and support for those affected by dementia.

For those dealing with this problem, knowing that there’s a supplement that might, just might, mitigate some of the memory loss, should be welcome news.

In my opinion, Vitality NAD+ Booster is worth a try.

SHOP NAD+ BOOSTER

Referenced Sources:

https://www.who.int/news-room/fact-sheets/detail/dementia ↩︎

NAD IV Therapy: How Often Should You Get It?

Written by Jinfiniti Science on August 28, 2024. Posted in NAD, NAD+. No Comments on NAD IV Therapy: How Often Should You Get It?

If you’ve already tried NAD IV therapy or are thinking about it, how do you know if it’s truly working for you?

If you’re not seeing the energy boost or vitality you hoped for, you might not be getting enough NAD from your current routine.

Read on to find out how NAD IV therapy works, why the frequency of your sessions matters, and whether it’s truly the right choice for you to achieve lasting energy and vitality.

In this article, we discuss:

How NAD IV therapy affects your body and whether your current routine is enough to keep you energized
How the right frequency can make or break your results
A simple yet more effective alternative to frequent NAD sessions that delivers long-lasting benefits at the cellular level

You’ve heard the buzz about NAD IV therapy and its powerful benefits—more energy, sharper focus, and a youthful glow.

But here’s the million-dollar question: How often should you get it to truly reap its benefits?

Too little, and you might not feel the full impact; too much, and you could be overdoing it.

The right frequency can boost your energy levels and support long-term vitality, helping you feel more focused and thriving daily.

What is NAD IV Therapy?

NAD IV therapy is a rejuvenating treatment that delivers a concentrated dose of nicotinamide adenine dinucleotide (NAD) into your bloodstream.

It’s a top pick for those who want to raise their NAD levels quickly, such as in cases of severe NAD depletion or chronic fatigue.

Low NAD levels can speed up cellular aging and mess with your energy production and DNA repair¹.

In NAD IV therapy, a sterile saline solution with NAD is slowly infused into your vein.

This method ensures that NAD is delivered directly to your cells without delaying absorption through the digestive system for more immediate results.

NAD IV therapy is known to boost energy levels, making you feel more vibrant and alive.

It also helps fight aging, promoting healthier skin, reducing wrinkles, and even improving sleep.

Beyond that, NAD IV therapy can enhance cognitive function, improve memory, and increase mental clarity.

Factors That Influence the Frequency of NAD IV Therapy

Everyone is different, so how often you should get NAD IV treatments can vary based on a few key factors, including…

Individual Health Goals

Your health goals play a major role in determining how often you should undergo NAD IV therapy.

Whether you’re targeting aging, boosting brain power, or recovering from a condition, you’ll need a different session frequency.

If you’re using NAD IV therapy mainly for anti-aging, you might need fewer treatments than someone using it for cognitive enhancement.

A personalized treatment plan that aligns with your specific goals is essential for getting the best results.

Current NAD Levels

Your baseline NAD levels are another crucial factor in determining how often you should receive therapy.

If your NAD levels are already low, you might need more frequent sessions to build them back up.

Conversely, if your levels are relatively high, less frequent treatments might be sufficient.

To get an accurate picture of where you stand, you can take an Intracellular NAD Test.

This test measures your NAD levels, helping you and your healthcare provider create a treatment plan that’s just right for you.

TEST YOUR NAD LEVELS TODAY

Age and Lifestyle Factors

As we age, our NAD levels naturally decline, making more frequent treatments beneficial.

Older adults may need more frequent NAD treatments² to restore and maintain optimal levels, while younger people might only need treatments every few months.

Additionally, factors like diet, stress levels, and lifestyle habits, such as exercise or lack thereof—can accelerate NAD depletion.

If your lifestyle is particularly demanding or your diet isn’t as balanced as it could be, you might need NAD IV therapy more often.

Overall Health and Medical Conditions

Your overall health and any underlying medical conditions also matter in deciding how often you should receive NAD IV therapy.

Chronic illnesses or certain health conditions may require more frequent treatments to see effective results.

For instance, those with neurodegenerative diseases might benefit from more regular NAD infusions³ over a more extended period to help manage their symptoms and improve their quality of life.

Your healthcare provider can help you determine the best approach based on your unique health needs.

Recommended Frequency for Different Goals

To hit your specific health goals, here’s a quick guide to the recommended NAD IV therapy frequency for different needs:

For General Wellness and Anti-Aging

If you’re looking to maintain overall health and slow the aging process, NAD IV therapy can be a powerful tool.

You might begin with three infusions every other week⁴, then move to a monthly maintenance session.

For the best results, many start with 1-2 sessions per week for the first 4-6 weeks⁵.

After that, a maintenance schedule of sessions every 4-6 weeks is usually recommended to keep NAD levels stable, supporting cellular repair and energy production.

For Cognitive Enhancement and Mental Clarity

The brain demands a lot of energy to function at its best.

If you’re looking to enhance cognitive performance or prevent decline, starting with a more frequent schedule, such as once or twice a week⁶ for the first month, is often recommended.

This can rapidly increase NAD levels in your brain, leading to better focus and memory.

After this initial period, you can reduce the frequency to one session every two to four weeks to keep your mind sharp.

For Athletic Performance and Recovery

Athletes and individuals who engage in intense physical activity can benefit from NAD IV therapy to enhance endurance and speed up recovery.

You might only need a few sessions throughout your training⁷ and then another right before big events like a marathon.

Once you’ve built up your NAD levels, you might reduce the frequency to once a month, maintaining peak performance and recovery.

NAD therapy aids in muscle recovery and reduces fatigue, helping you perform at your best.

For Chronic Conditions or Severe NAD Depletion

If you’re dealing with a chronic illness or have significant NAD depletion, more frequent NAD IV therapy sessions may be necessary.

In these cases, starting with two to three sessions per week⁸ can provide the needed boost to your NAD levels, helping manage symptoms and support overall recovery.

As your condition improves, you may gradually reduce the frequency of treatments.

However, maintaining regular sessions, such as once a week or bi-weekly, can be crucial for long-term management of chronic conditions.

NAD IV Therapy vs Oral NAD Supplement: Which Works Best?

When boosting your NAD levels, both NAD IV therapy and oral supplements can get the job done—but which one is right for you?

If you’re looking for a quick, powerful boost—perhaps to address more severe symptoms—NAD IV therapy might be the way to go.

However, it’s not without its drawbacks.

Because the NAD+ molecules are too large to pass through cell membranes on their own, this method primarily benefits the bloodstream, only offering a rapid boost.

However, a study published by Frontiers in Aging Neuroscience found that NAD levels in the blood plasma didn’t increase until a few hours into the infusion.

Initially, NAD broke down in the first two hours, so it had little effect on blood levels⁹.

Plus, NAD IV therapy can be expensive—around $200 per session—and if your treatment plan calls for multiple sessions a week, the costs can add up quickly.

On the flip side, oral NAD supplements offer a more gradual and cost-effective approach.

These supplements usually have NAD precursors, such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), which your body converts into NAD+.

While they might not give you the quick burst of energy that IV therapy can, they’re very effective for delivering benefits directly at the cellular level.

Over time, these supplements support sustained energy, better metabolism, and overall health from within.

They’re also easier on the wallet and more convenient for daily use.

TEST YOUR NAD LEVELS TODAY

Referenced Sources:

What is NAD IV Therapy and Should You Consider It?

Written by Jinfiniti Science on August 26, 2024. Posted in NAD, NAD+, Popular. No Comments on What is NAD IV Therapy and Should You Consider It?

In upscale wellness clinics and medical spas across America’s affluent neighborhoods, a new kind of intravenous treatment has gained prominence among those seeking the latest in regenerative medicine. NAD IV therapy – or intravenous NAD therapy – represents a growing trend in the world of alternative wellness treatments, where patients receive the vital cellular compound Nicotinamide Adenine Dinucleotide (or NAD) through direct intravenous administration.

NAD is a coenzyme found naturally in every cell of the human body, playing a key role in cellular function and energy production. Often called a “helper molecule,” it assists in hundreds of metabolic processes, particularly in converting food into cellular energy and maintaining healthy DNA.

In this article, we’ll cover:

What NAD IV therapy is and how it works to deliver NAD+ directly into the bloodstream
The potential benefits of NAD IV therapy, from addiction recovery and cognitive enhancement to anti-aging and cellular health optimization
The safety considerations, side effects, and costs associated with NAD IV infusions
How NAD IV therapy compares to oral NAD supplements in terms of efficacy, convenience, and scientific support

What is NAD IV Therapy?

NAD IV therapy, sometimes referred to as NAD infusion or IV drip, typically takes place in medical clinics or specialized wellness centers, where patients recline in comfortable chairs for sessions lasting anywhere from two to four hours. A healthcare provider inserts an IV line into the patient’s arm, connecting them to a drip containing a solution of NAD+ (the oxidized form of NAD) mixed with saline.

The lengthy duration of the treatment isn’t due to the volume of fluid – rather, it’s intentionally slowed to minimize the side effects that can occur with rapid administration. Some clinics offer private rooms equipped with entertainment systems and other amenities to help pass the time.

What began as a niche treatment in high-end coastal clinics has expanded into a nationwide phenomenon. Prices typically range from several hundred to over a thousand dollars per session, with many practitioners recommending initial protocols of 4-10 treatments followed by periodic maintenance sessions.

Medical spas, integrative medicine clinics, and even traditional medical practices have begun offering NAD IV therapy. NAD treatment has found particular popularity in wealthy enclaves from Beverly Hills to the Hamptons, where it joins a growing menu of wellness interventions aimed at an affluent clientele.

The therapy exists in a regulatory gray area – while the administration of IV treatments requires medical supervision, the NAD compounds themselves are typically obtained through compounding pharmacies. Practitioners range from medical doctors to naturopathic physicians, depending on state regulations regarding IV therapy administration.

Unlike traditional medical treatments, NAD IV therapy often operates in the cash-pay market, outside the usual insurance frameworks. This has contributed to its reputation as a luxury wellness service rather than a conventional medical treatment.

In clinics across the country, practitioners present this therapy as part of a broader approach to cellular health and regeneration, positioning it alongside other emerging treatments in the rapidly expanding field of longevity medicine.

Takeaway: NAD IV therapy is a lengthy (2-4 hour) intravenous treatment administered in medical clinics and wellness centers, where NAD+ mixed with saline is slowly dripped into patients to minimize side effects.

Does NAD IV Really Work to Increase NAD+ Levels?

When discussing treatments to increase NAD+, it’s important to understand the distinction between intracellular (iNAD+) and extracellular (eNAD+) forms, since they have dramatically different concentrations and roles.

Intracellularly, NAD+ is abundant, typically ranging from micromolar to millimolar concentrations¹. In contrast, extracellular NAD+ levels are remarkably low, measuring approximately 500 times less concentrated than intracellular levels².

When NAD is administered intravenously, it primarily affects extracellular NAD+ levels. Research demonstrates that IV NAD+ infusion has minimal direct impact on intracellular NAD+ concentrations. In fact, studies show that during a continuous NAD+ infusion, plasma levels only significantly increased at the 6-hour mark, with a 398% rise relative to baseline³.

The body does not directly incorporate IV NAD+ into cellular NAD+ pools. Instead, metabolites like nicotinamide (NAM), nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN) can potentially enter cells and be used to regenerate NAD+⁴.

Recent research indicates that IV NAD+ may not significantly elevate whole blood NAD+ levels within 24 hours, suggesting limited cellular penetration and utilization⁵. This underscores the complexity of directly increasing cellular NAD+ through IV administration.

Moreover, our own research at Jinfiniti has found that NAD IV therapy does not significantly increase NAD levels inside the cells for several reasons.

First, the amount of infused NAD+ and the frequency of infusions do not provide sufficient NAD+.
Second, NAD+ is rapidly degraded in the bloodstream within hours.
Third, the NAD+ molecule is too large to penetrate the cells.

Take a look at the graph below.

The use of 750 mg of intravenous NAD+ infusion over 5 sessions did not increase intracellular NAD levels (indicated by the blue bars in the chart).

Meanwhile, oral NAD supplementation for four weeks optimized NAD levels in 7 of 8 test subjects and significantly boosted NAD in others (indicated by the green bars in the chart).ur weeks optimized NAD levels in 7 of 8 test subjects and significantly boosted NAD in others (green bars).

This suggests that NAD+ infusions may not be an ideal option for those looking to increase energy, improve performance, or extend longevity.

Takeaway: IV NAD+ therapy primarily affects extracellular NAD+ levels but has minimal direct impact on intracellular NAD+ concentrations.

Potential Benefits of NAD Therapy

While the jury is still out in the scientific community on the full scope of NAD IV therapy’s effectiveness, proponents of this treatment cite a range of potential benefits that have attracted a dedicated following among wellness enthusiasts and those seeking alternative approaches to health optimization. These benefits are mostly attributable to an increase in NAD+ levels, which, as mentioned above, is more nuanced than some may think.

Addiction Recovery

Clinical studies on NAD+ IV therapy for addiction remain limited, but one review indicates potential as an anti-addiction intervention by addressing multiple neurobiological aspects of addiction. Previous clinical reports have documented benefits of IV NAD+ infusion in alcohol and opioid withdrawal, with researchers observing significant improvements in reducing cravings and alleviating withdrawal symptoms⁶.

Energy and Metabolism

Practitioners report that many patients seek out NAD therapy primarily for its effects on energy levels. The treatment’s supporters point to NAD’s fundamental role in cellular energy production⁷, likening it to recharging a battery at the cellular level. Some clinics report that patients experience increased energy levels lasting days or even weeks following treatment.

Cognitive Function

In Silicon Valley boardrooms and Wall Street offices, executives have turned to NAD therapy in pursuit of supercharged mental clarity. Advocates suggest that the treatment may support brain function by helping maintain healthy neurons and potentially reducing inflammation⁸. Some patients report experiencing improved focus and mental acuity, though these effects remain largely anecdotal.

Athletic Recovery

Professional athletes and fitness enthusiasts have embraced NAD therapy as part of their recovery protocols. The treatment’s proposed ability to support cellular repair and energy production has made it popular among those seeking to optimize their physical performance and reduce recovery time between intense training sessions.

Age-Related Concerns

Perhaps the most intriguing area of interest lies in NAD’s role in aging. Research has shown that NAD levels naturally decline with age⁹, leading some scientists to investigate whether restoring these levels might influence the aging process. The potential anti-aging effects of NAD IV have certainly captured the attention of the longevity medicine community and warrant further exploration.

Cellular Health

Proponents believe that NAD IV therapy may help support overall cellular health by improving mitochondrial function – the energy-producing centers within cells. This could potentially have wide-ranging effects on various aspects of health, from metabolism to tissue repair.

Metabolic Function

Clinics report that some patients seek NAD therapy for its potential to support healthy metabolism. The treatment’s role in cellular energy production has led to speculation about its effects on metabolic health, though research in this area continues to evolve.

How Safe is NAD IV Treatment?

While many practitioners consider the treatment generally safe when administered properly, patients should be aware of various side effects and safety considerations before pursuing IV infusion.

During IV NAD therapy sessions, patients frequently report a range of temporary symptoms that typically subside once the infusion is complete or shortly thereafter:

Chest tightness or discomfort
Moderate to severe headache
Shortness of breath
Nausea and stomach discomfort
Flushing of the face
Racing heart or palpitations
Anxiety or jitteriness
Mild dizziness
Temporary changes in vision

The speed of NAD administration plays a significant role in the intensity of side effects. Experienced practitioners typically begin with lower doses and slower infusion rates, gradually increasing them based on patient tolerance. This approach, while extending treatment duration, helps minimize adverse reactions.

NAD IV therapy has been observed to elevate high-sensitivity C-reactive protein (hs-CRP) levels, with approximately 70% of recipients showing a 3- to 10-fold increase in this inflammation marker. Given these effects, monitoring hs-CRP and implementing inflammation control measures is recommended for patient safety.

Medical professionals stress that NAD IV therapy should only be administered in appropriate clinical settings with proper medical supervision. The treatment requires careful screening of patients for underlying health conditions that might contraindicate its use.

Certain populations may face higher risks when receiving NAD therapy. People with kidney or liver conditions, heart problems, or those taking specific medications should exercise particular caution. Pregnant or nursing women are typically advised to avoid the treatment due to limited safety data.

The medical community notes that while short-term side effects are well-documented, the long-term safety profile of regular NAD IV therapy remains under investigation. Some healthcare providers express concern about the lack of extensive longitudinal studies examining the effects of repeated treatments.

The rapidly growing NAD therapy industry has raised concerns about quality control and standardization. The source and purity of NAD compounds can vary between facilities, potentially affecting both safety and efficacy. Patients are advised to thoroughly research facilities and verify the credentials of practitioners administering the treatment.

Takeaway: NAD IV therapy can cause temporary side effects like headaches and nausea, with severity depending on infusion speed and individual tolerance. While generally considered safe under proper medical supervision, certain populations face higher risks, and long-term effects remain under study.

How Much Does NAD IV Therapy Cost?

NAD IV therapy costs can vary widely based on dosage, location, clinic expertise, and additional treatments. On average, the cost ranges from $200 to $1,000 per session. For longer-term treatment plans, costs can accumulate significantly. Many providers recommend multiple sessions over several days or weeks for optimal results, which can drive up the total expense. For example, a series of treatments over 2-3 days could cost $1,500 to $3,000 or more.

Some clinics offer package deals or membership options for regular treatments, which may provide some cost savings for ongoing therapy. It’s also important to note that NAD IV therapy is generally not covered by insurance, as it’s considered an elective treatment.

Is NAD IV FDA-Approved?

NAD IV therapy is not FDA-approved for the treatment of any specific condition. This does not mean the treatment is illegal or unsafe when administered properly. NAD therapy falls under the category of dietary supplements, which are not required to undergo FDA review for safety or effectiveness before being marketed. The FDA has acknowledged NAD therapy’s potential efficacy for treating certain conditions like benzodiazepine dependence, opiate withdrawal, and chronic fatigue, though it has not formally approved it.

NAD Infusions vs Oral NAD Supplements

NAD supplementation offers two primary approaches: oral NAD supplements and IV therapy, each with distinct advantages for individuals seeking to boost cellular energy and combat aging. Oral supplements provide a convenient, cost-effective method for gradually increasing NAD+ levels, with studies showing potential increases up to 142% after two weeks of consistent use¹⁰. These supplements are typically more affordable, ranging from $20 to $150 per bottle, and can be easily integrated into daily routines.

In contrast, intravenous therapy delivers a rapid, direct NAD+ boost directly into the bloodstream, making it potentially more suitable for acute health conditions or intensive recovery needs. However, this method comes with significant drawbacks, including the higher costs and potential side effects outlined above.

It’s worth noting that the majority of peer-reviewed studies have focused on oral NAD+ supplements rather than intravenous delivery. This research disparity stems from several practical factors. Oral supplement studies offer advantages in scientific settings: they’re easier to control, more cost-effective to conduct, and more practical for the large-scale, long-term trials needed to establish clinical efficacy. Major research institutions have primarily concentrated their investigations on oral NAD+ precursors such as NMN and NR.

Many of the benefits attributed to IV NAD+ therapy are extrapolated from studies on oral supplements, which often have different bioavailability and physiological effects. This disconnect has led some researchers to call for more rigorous investigation of the IV delivery method, particularly given its growing popularity and higher cost compared to oral alternatives.

Takeaway: Oral supplements are backed by more extensive research and clinical trials, while IV therapy’s effects are less thoroughly studied despite its growing popularity.

Should You Get NAD IV Therapy?

When considering IV therapy, it’s important to carefully weigh the potential NAD+ benefits against the risks, costs, and limitations. While many individuals report positive experiences with this treatment, the scientific evidence supporting its efficacy remains limited compared to well-studied oral NAD supplements.

The allure of a rapid NAD boost via IV infusion is understandable, particularly for those facing acute health challenges or seeking accelerated recovery. However, the higher costs, potential side effects, and lack of long-term safety data should give pause to anyone considering this approach.

In contrast, oral NAD supplements offer a more accessible, affordable, and scientifically validated option for gradually increasing NAD levels over time. With a growing body of research supporting their safety and efficacy, these supplements may represent a more prudent choice for the majority of individuals seeking the benefits of NAD therapy.

Ultimately, the decision to pursue NAD IV therapy should be made in close consultation with a trusted healthcare provider who can assess your individual needs and risk factors. They can help you evaluate whether the potential benefits outweigh the risks in your specific case, and guide you toward the most appropriate options for supporting your health and well-being.

For those interested in a clinically proven, convenient, and cost-effective alternative to IV therapy, Jinfiniti’s Vitality ↑® NAD+ Booster stands out as a compelling option. This patent-pending oral supplement combines four powerful ingredients – NMN, creatine monohydrate, D-ribose, and nicotinamide – to optimize NAD levels through multiple pathways.

Vitality’s unique formulation includes both a one-step NAD precursor and supports the salvage pathway that recycles nicotinamide, while creatine monohydrate serves as an ATP energy reservoir and potential neurotransmitter. All ingredients are third-party tested for the highest purity, ensuring a safe and effective way to revitalize cellular function without the risks and costs associated with IV therapy.

DISCOVER NAD+ BOOSTER

Referenced Sources:

How NAD Gave My Dog Six More Months Of Health, Happiness, And Life

Written by Jinfiniti Science on August 20, 2024. Posted in Longevity, NAD, NAD+.

Those of us who choose to lead a healthy lifestyle are keenly aware that diet, exercise, supplementation, quality sleep, and stress management are key components on our path.

Those of us who are pet owners also want our pets to enjoy the same good health and long life that we envision for ourselves.

I’d like to share my Romeo the Red toy poodle’s senior year NAD supplementation story…

… so that others’ dogs may benefit from what I learned as I faced health challenges for Romeo.

There’s a saying that I read months after Romeo passed and it touched me deeply: “A dog might only be there for part of your life, but to them, you are their entire life ”

Wow! That one floored me.

For us, a dog might be one aspect of a busy life filled with work, family, and countless other commitments. But to our dogs, we are everything—their world revolves around us, and their loyalty, love, and devotion are unwavering.

Nowhere is this more evident than every time we return home to an excited, loving greeting from our loyal companion, who has waited patiently for our return.

The jumping, the tail wags, the unbridled excitement that we are “back” is a constant reminder that we are loved and missed, even for short periods of time.

Dogs teach us the true meaning of unconditional love.

They don’t care about our flaws or mistakes; to them, we are perfect. This kind of love is rare, and it’s why the bond we share with our dogs is so special.

They remind us to live in the moment, to appreciate the simple joys of life, and to always greet the people we love with enthusiasm and warmth. In return for their boundless love, we owe them our time, attention, and care—because while they may be just a part of our lives, we are their whole world.

Perhaps the most important role in our dog’s life is that of steward of their health.

We decide what they are going to eat, where they will go, and upon which bed or floor they will sleep. It is on us to make sure their lives are safe, comfy, and secure.

Their very lifespan, for the most part, is in our hands. Ensuring that our pet lives as many years as possible before the Rainbow Bridge crossing becomes a challenge that we take seriously once conditions dictate that we recognize that we will live on but our furbaby will not.

My red toy poodle Romeo finally began, at about age 12, to show his first symptom of aging.

I say “began” because up until that point, people often mistook him for a puppy.

However, this day when he went outdoors for his midday walk, he took a few steps and then just stopped. He began to flinch and jerk backward, reacting to “something.”

I pulled gently on his leash, but he just stood there, his head jerking side to side rapidly, as though he was in pain.

He continued to back away, not proceeding forward, clearly in distress. I assumed he was having some sort of seizure. I’d had a Yorkie named Missy who lived to 17 ½.

In Missy’s last years, she became epileptic and seizures were a common occurrence. This was new for Romeo and scary for both of us.

I picked him up off the pavement and jumped into my car, racing him to the doggie ER nearby.

Those of you who have endured a dog healthcare emergency of any sort know well the anguish, fear, and stress that send your heartbeat racing and cortisol levels soaring.

This event happened during Covid and lockdown measures and my stress was further exacerbated by having to hand my poor, shaking little fluffball off to an attendant for transport to the vet’s exam room.

After what seemed like an eternity, Romeo and I were reunited in the vet’s waiting room.

Once outside and in the car, I received the promised telephone follow-up call from the vet. (Again, this was during Covid and personal contact was limited, if allowed at all.)

I was informed that Romeo’s ailment was not epilepsy and that he had not suffered a seizure. The vet diagnosed the condition as one in his eyes.

His irises were atrophied and the flinching and jerking away movements were from sunlight straining his eyes.

He had become extremely light-sensitive. From that point on, nearly any amount of sunlight would cause him extreme discomfort.

Like many of the symptoms of aging in humans, this new condition had shown up in my dog seemingly overnight. (I remember my vision devolving significantly the night of my 4oth birthday.

I went to bed with 20/20 vision and woke up with presbyopia. At least that’s how it seemed.)

That eye diagnosis marked the beginning of Romeo’s new dog walk program.

I had to walk him in the early morning or late in the day. If I popped out midday to run an errand, I made sure to shield his eyes while driving in the car during daylight. I had suddenly become the official Steward of Senior Dog Health, a mantel I happily assumed.

As with all slippery slopes, Romeo’s aging started slowly but gained speed with time. I began to search in earnest for doggie longevity products and ways to keep him agile and aware.

I was so proud when, even at age 14, people still mistook him for a puppy. I loved the look of shock on their faces when I told them his age.

Still, rainy days were anathema to his joints. Running up and down stairs one day would result in some hobbling and stiffness the next. I tried little grip booties to keep his legs from sliding out from under him on slippery floors. Getting up and down out of his dog bed became a chore.

It was a few months into his 14th year that his arthritis took a heavier toll.

He was achy and listless many mornings when we prepared for his first walk of the day. Clearly, he was experiencing serious joint pain that affected his mobility.

That last year saw Romeo having bladder control issues. Perfectly housebroken for years, he began to have accidents if he wasn’t walked every two hours.

My work and personal life were adjusted to ensure that I, or occasionally someone else, could walk him constantly. Yes, I set my alarm and got up in the middle of the night to walk him as well.

Non-dog people told me things ranging from…

“He’s just a dog, time to let him go” to “You have a life to live, it’s too much.”

But I soldiered on, as did Romeo.

He was a proud boy and having accidents embarrassed him.

His GI tract became problematic and there were bouts of diarrhea that were not fun for either of us. Eventually, his energy level declined to the point that he was sleeping most of the day and worn out or too stiff for the most brief walks.

Halfway into that last year, after an emergency vet visit for extreme diarrhea and total loss of appetite (a confusing combination, to say the least)…

My lovely vet lady pulled me aside and suggested that it might be time to make “the decision.”

I began to cry and she wanted to console me. “Well,” she said, “It might not be today. But it reasonably could be.”

I looked her deeply in the eye and asked her, “How do you know? “

I don’t want to play God.” She answered,

“He’s not eating. He’s in pain. His organs are beginning to fail. “

I had told her what our schedule had become, the every two-hour walks night and day, the constant cleaning up of “problems” and more.

With all that in mind, she said, “The truth is, at some point one of you is going to give up.“

I looked her squarely in the eye, tears streaming down my face, and said, “But today is not that day.”

We went home, little Romeo and I. That night, I had an idea.

I had been taking Vitality ↑® NAD+ Booster for about a year and a half. I knew the benefits I was enjoying. I’d seen it work wonders for friends and family who had issues ranging from allergies to lack of energy to brain fog to inflammation.

I called Dr. Jin-Xiong She and somewhat brusquely asked him, “Why can’t I give my senior dog Romeo Vitality ↑® NAD+ Booster?”

He paused only briefly before answering, “You can!”

That night I sprinkled the NAD precursor powder cocktail Vitality ↑® NAD+ Booster on Romeo’s food.

This is the dog who had turned his nose up at anything I had bought or prepared for him for at least a month.

I purchased high-end gourmet dog foods that cost a fortune.

I put him on a subscription for fresh dog food delivered to the door. I cooked for him more than I did for myself. He would take a sniff, turn away, and slowly walk back to his bed to fall asleep again.

He was skin and bones.

However, that night, after I placed his bowl back on the floor and walked away, something amazing happened.

Romeo did the same sniffing he had been doing for weeks. He poked with his nose and smelled the powder-covered dog food.

He gave a perfunctory lick to the top of the food in the bowl. And then he ate. He ate and he ate.

He finished the bowl.

I’d love to say that he jumped up on his hind feet and did a little doggy jig, but he did not.

He did, however, get back into his bed and fall asleep.

The next morning Romeo once again ate the food with the Vitality ↑® NAD+ Booster added.

When we went for our walk, he had the hint of a spring in his step.

Over the next weeks, he continued to eat and enjoy the food/NAD combo, twice a day, a half doggy dose.

The thing that made me most happy was when, upon returning from a walk, he did what he had not done for months: he raced down the hallway from the elevator in our building to the front door of our condo.

That little run had been one of the cutest things ever for years and it always brought a smile to my face. It was like he was running the Derby and in the last stretch determined to beat the rest of the racers.

He would land in front of our door and turn to me sit back on his haunches and look at me as though to say, “What’s taking you so long, slowpoke?”

I have videos of Romeo making that run again in his last year after months of a slow drag back home.

My little red boy crossed the Rainbow Bridge six months after his vet had suggested it might be time.

Vitality ↑® NAD+ Booster gave him six months of reasonable health, happiness, and life.

I had known that his journey to that Bridge was not far off on the horizon, but it was still a surprise the morning it came.

My friend Sabrina had a cute little girl (Jazzy) like my Romeo, and she had had to let Jazzi cross the bridge a few weeks before Romeo did.

Yet another friend of mine, a bestie from grade school, had arrived home after work a few months before to find that her rescue dog had passed in her absence.

These had both prepared me to some degree, but the last day with a pet is always loaded with shock and sadness.

What comforted me was knowing that the last six months Romeo lived were made possible and were more comfortable thanks to Jinfiniti Precision Medicine’s Vitality ↑® NAD+ Booster.

My next dog will be given his Vitality ↑® NAD+ Booster daily from the moment I bring him/her home.

SHOP NAD+ BOOSTER

Is NAD a Healthy Weight-Loss Alternative to Ozempic?

Written by Jinfiniti Science on August 13, 2024. Posted in NAD, NAD+, Obesity and Weight Gain.

NAD+ overcomes insulin resistance without disastrous side effects.

Social media is burning up with images of celebrities who’ve dropped significant tonnage, but are mute about their methods.

This is an odd phenomenon, given the characteristic eagerness of this class to publicly pledge their allegiance to the newest fad, no matter how bizarre that craze might seem to the average person on the street. Yet, at each exhibition of luminary lipid loss, the same word is uttered in hushed whispers: Ozempic.

And we have to wonder, why the muted tones? If Ozempic is a miracle weight-loss drug, shouldn’t we be shouting about it from the rooftops? Turns out there are ample reasons to be wary, and even more reasons to choose a particular safe and effective alternative: the natural coenzyme NAD.

Step 1: Design a catchy ad campaign

Want to charge $1,200 a month for an injection whose benefits are decidedly short-term, and which puts patients at risk for numerous painful, debilitating side-effects, as well as a dispiriting rebound of the conditions they sought to alleviate in the first place? Then you must, must, must pick a catchy, long-forgotten pop song from the 1970s, whose original lyrics were all about the wondrous state of being in love.

Now you’ve got “Oh-oh-oh-Ozempic!” subliminally telling viewers of ubiquitous pharma commercials that “It’s magic.” Fossils of my era will remember the Scottish band Pilot cautioning listeners, “Never believe it’s not so!” But should we believe the advertising hype around Ozempic? Many sources, including those in the health and fitness sphere outside of Big Pharma, are telling us “No.”

What is Ozempic and why should I be skeptical?

According to the website Health.com¹, Ozempic a semaglutide, a “synthetic version of a human hormone called glucagon-like peptide one, or GLP-1.” Humans secrete GLP-1 when food reaches our gut.

It tells our brain that we’re full and tells our pancreas to get off the schneid and produce some insulin, the hormone that signals our cells to open wide and receive blood glucose.

When all works well, GLP-1 ensures that we don’t gorge ourselves and that the vacuoles of our cells widen, taking in glucose to convert to energy. This latter process also lowers our blood glucose levels, sparing us the consequences of diabetically high blood sugar.

People with type II diabetes either don’t produce enough insulin or suffer from extreme insulin resistance, so that while their insulin’s a knockin’, their vacuoles are sayin’ “Don’t come in.” (This is a problem with cell-signaling, one of the many cellular functions that depend heavily on the co-enzyme nicotinamide adenine dinucleotide, or NAD.)

Ozempic is designed to increase insulin production for type II diabetics who have had trouble getting their blood sugar under control with other methods. Ozempic is delivered via twice-monthly injections, at a cost of about $1,200 per month.

Health.com tells us, “After injection, semaglutide increases insulin production and lowers blood sugar. This causes the stomach to empty more slowly, reduces appetite, and makes people feel full.” So, it should come as no surprise that Ozempic has delivered another sought-after benefit: weight loss.

Is the bonus benefit just a dangerous illusion?

The Ozempic bonus has led overweight people, especially celebrities who can afford the high price tag, to request the drug for weight loss, a use for which the FDA has not approved it.

Yet, doctors seem willing to prescribe Ozempic for off-label use, a practice that is often controversial if not illegal. In fairness to these doctors, we should note that another semaglutide prescription, Wegovy, has FDA approval as a weight-loss drug. But should either of these synthetic hormone drugs be used for this purpose?

This lady in a lab coat says no. And we must listen because she is appropriately dressed. (Also note that she’s an MD, not an actress.)

Thank you, Dr. Annette Bosworth.

A litany of side-effects, some of which are deadly

If you’ve seen an O-O-O-Ozempic commercial, you’ve heard the recitation of side effects, which range from unpleasant to deadly. The mild variety includes:

Fatigue
Dizziness or vertigo
Discomfort and/or skin discoloration around the injection site
Increased heart rate
Changes in perception of taste
Digestive problems, such as belly pain, constipation, diarrhea, flatulence, burping, nausea, and vomiting

Ozempic patients have also started reporting hair loss².

The more serious side effects include:

Kidney problems, such as kidney failure
Low blood sugar
Pancreatitis
Gallbladder disease, such as cholecystitis or gallstones
Thyroid cancer
Allergic reactions

All of these are potentially fatal.

After reading these lists, the reasonable reader might wonder, “At what point do the risks outweigh the possible benefits?” For people who cannot control their diabetes, the disease is eventually fatal.

Other messy consequences include blindness and amputation of extremities. So, a roll of the dice with Ozempic might be in order.

Alternatives to a potentially deadly roll of the dice?

However, most people with type II diabetes can control their sugar through dietary and lifestyle modification. These changes are generally not easy, which is why many so people are open to taking a magic shot, courtesy of our consistently trustworthy friends at Big Pharma.

This mindset, which seems to be the basis for Ozempic’s marketing strategy, has really rankled celebrity trainer Jillian Michaels, who has voiced her concerns about Ozempic to Megyn Kelly (video below) and Bill Maher.

As Ms. Michaels explain, Ozempic treatment is necessarily short. And for many patients, the benefits sunset early, as their weight loss plateaus and the pounds rebound. Unfortunately, the side-effects seem to linger³ well beyond patients’ use of the drug.

Another reason for concern is the psychological effect Ozempic seems to have on type II diabetics, who should maintain a strict exercise regimen. According to a report from MSN, Ozempic seems to discourage overweight people from working out⁴.

Is NAD+ optimization a better way to manage insulin resistance?

Dr. Jin-Xiong She is a prominent microbiologist who has spent a significant portion of his career studying the relationship between cellular functions and age-related/metabolic diseases, including type II diabetes.

The precursor to type II diabetes is the condition we call insulin resistance, where the cells do not respond to the insulin’s signal.

This forces the pancreas to produce more insulin, eventually exhausting itself. When the body no longer produces its own insulin, a patient must take insulin orally or via injection. For people in a prediabetic state, insulin resistance causes stubborn weight gain, along with ancillary health problems.

Dr. She has studied the role of NAD in cellular functions, and in this short video, he explains four key benefits of NAD as they pertain to normal insulin sensitivity.

Unfortunately, people lose NAD due to age, stress, and lifestyle choices, such as a poor diet, smoking, alcohol consumption, and a sedentary lifestyle.

This can turn insulin sensitivity into insulin resistance. The good news is that replenishing lost NAD can return the system to healthy homeostasis. Replacing lost NAD is tricky, but Dr. She has developed a highly effective supplement he calls Vitality ↑® NAD+ Booster.

SHOP NAD+ BOOSTER

NAD optimization: a safe, natural path to better health

One of the great benefits of Vitality ↑® NAD+ Booster is the increased energy one feels after just a few days of using the product. This can empower an overweight person with insulin resistance or type II diabetes to hit the gym and get the natural health benefits of exercise.

Many people have been able to reverse type II diabetes and return to good health through dietary and lifestyle modifications. Supplementing to achieve NAD optimization makes the process easier, so more patients should be able to improve their health for the long term.

Importantly, NAD is a natural compound, not a synthetic, so there’s no list of horrendous side effects. I’ve written in this column⁵ about the numerous health benefits I’ve experienced with Vitality ↑® NAD+ Booster. It’s precisely because of those health benefits that I asked Dr. She to make me an affiliate marketer for his company Jinfiniti Precision Medicine.

If you are struggling with insulin resistance or type II diabetes, I urge you to try this amazing product. Ask your doctor which is more likely to help you: the all-natural compound that’s an essential cofactor for virtually every cellular function, or the synthetic hormone with the catchy jingle, a monthly cost equal to your mortgage, and a list of side effects the length of the King James Bible.

O-O-O-I think I know what they’ll say.

Great news: Get started with NAD for only $28!

Vitality ↑® NAD+ Booster has never been more cost-effective than now, because Dr. She is offering an introductory, one-month supply for only $28 dollars with a monthly subscription. That’s a savings of 76 percent, and you can cancel the subscription any time, if you’re not thrilled with the results. Just follow this link: Start for $28!

Disclaimer: The column may contain affiliate links, which help support the website. When you clink on an affiliate link and make a purchase, the website receives a small commission at no additional charge to you. Thank you for your support.

Kevin Rush is an award-winning playwright and screenwriter. He’s the author of three novels, including The Lance and the Veil, an adventure in the time of Christ (which Kirkus Reviews calls “a big, bold Biblical saga to fire the Christian imagination”) and The Wedding Routine, (hailed by Online Book Club as a 4/4 Star romantic comedy delivering “nothing but comic gold”). Learn more at www.kevinrush.us.

SHOP NAD+ BOOSTER

Author: Jinfiniti Science

Understanding the Importance of NAD+

The Causes of NAD+ Decline

Natural Ways to Boost NAD Levels

Dietary Approaches

Exercise and Physical Activity

Lifestyle Changes

Heat Exposure

Supplements to Increase NAD Levels

Advanced NAD Therapies

How to Monitor Your NAD Levels

Test Your NAD Levels with Jinfiniti

Referenced Sources:

What is NAD IV Therapy?

Common Safety Concerns of NAD Therapy

Infection

Vein Irritation

Incorrect Dosage

Improper Administration

Quality and Sourcing of NAD Products

What are the Side Effects of NAD IV Therapy?

Common Short-Term Side Effects

Possible Long-Term Side Effects

The Safest Approach to NAD IV Therapy

Choose a Qualified Provider

Evaluate Your Health

Monitor Your NAD Levels Regularly

Oral NAD Supplements: A Safer Alternative to NAD IV Treatment

Final Thoughts: Is NAD IV Therapy Safe?

Referenced Sources

Are NAD and NADH the Same?

Key Differences Between NAD and NADH

Oxidation and Reduction

Chemical Structure and Properties

Biological Functions

NAD+/NADH Ratio

NAD+ and NADH in Aging and Disease

NAD+ and NADH in Energy Production

NAD+ and NADH in Cellular Signaling

Measurement and Detection Methods

NAD+ and NADH in Health and Wellness

Is It Better to Supplement NAD+ or NADH?

Test Your NAD Levels with Jinfiniti

Referenced Sources:

Why Does NAD IV Therapy Take 4 Hours or More?

Top Immediate Benefits After NAD IV Therapy

Increased Energy

Mental Clarity

Better Mood

Improved Focus

Is NAD IV Worth Four Hours of Your Time?

Is There a More Efficient and Faster Alternative to NAD IV?

Is NAD IV Therapy Worth It or Not?

Referenced Sources:

What is NAD IV Therapy?

How Much Does NAD IV Therapy Cost?

Additional Fees

Cost of Multiple NAD Therapy Sessions

Is NAD IV Therapy Covered by Insurance?

NAD IV Therapy vs Oral NAD Supplement Cost

Is the Cost of NAD IV Therapy Worth It?

Referenced Sources

I was surprised when my dear friend’s cognition declined dramatically overnight at age 94.

When my dear friend reached and passed his 90th birthday with a mind sharp as a tack I assumed he was all clear.

Marshall’s great mind and good memory were perfectly intact until one fateful day.

From one day to the next my friend had forgotten how to use both his cellphone and his computer.

A battery of cognitive tests with a gerontology professional confirmed that he was experiencing mild to moderate dementia.

What if Vitality NAD+ Booster, a NAD supplement formula and known neurotransmitter, could help?

At least 50-65% cognitively recovered.

He knows how to use his phone, he’s back at the computer, those bathroom issues are pretty much gone, and he’s using his walker and cane as well as he formerly had.

He is now back in charge of his meds and supplements because he began to remind me to give him doses as he remembered what to take and when.

Referenced Sources:

What is NAD IV Therapy?

Factors That Influence the Frequency of NAD IV Therapy

Individual Health Goals

Current NAD Levels

Age and Lifestyle Factors

Overall Health and Medical Conditions

Recommended Frequency for Different Goals

For General Wellness and Anti-Aging

When my dear friend reached and passed his 90^th birthday with a mind sharp as a tack I assumed he was all clear.